Description

Methanone, (4-Chlorophenyl)(1-((2,3-Dihydro-1,4-Benzodioxin-2-Yl)Methyl)-4-Piperidinyl)-, Hydrochloride is a high-purity pharmaceutical intermediate and research chemical. This compound is valued for its role as a key synthetic building block in the development of active pharmaceutical ingredients (APIs). It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the synthesis and scale-up of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of complex drug molecules, particularly in central nervous system (CNS) and cardiovascular research.
• Active Pharmaceutical Ingredient (API) Development: Serves as a core structural component for novel therapeutic candidates undergoing preclinical and clinical evaluation.
• Biochemical Research: Used in pharmacological studies to investigate receptor binding affinity and mechanism of action.
• Process Chemistry & Scale-Up: Employed in route scouting and optimization for the commercial manufacturing of target compounds.
• Reference Standard: Provides a high-purity standard for analytical method development, validation, and quality control in pharmaceutical analysis.

Basic Information

Product Name	Methanone, (4-Chlorophenyl)(1-((2,3-Dihydro-1,4-Benzodioxin-2-Yl)Methyl)-4-Piperidinyl)-, Hydrochloride
CAS No.	76362-14-6
Molecular Formula	C21H22ClNO3·HCl
Molecular Weight	416.32 g/mol (for free base: 379.86 g/mol)
Synonyms	1-[(2,3-Dihydro-1,4-benzodioxin-2-yl)methyl]-4-(4-chlorobenzoyl)piperidine hydrochloride; 4-(4-Chlorobenzoyl)-1-[(2,3-dihydro-1,4-benzodioxin-2-yl)methyl]piperidine hydrochloride; (4-Chlorophenyl){1-[(2,3-dihydro-1,4-benzodioxin-2-yl)methyl]-4-piperidinyl}methanone hydrochloride; 76362-14-6; UNII-2C4V7J7T8I; 2C4V7J7T8I
EINECS	Contact for details

Quality Control

Our Methanone, (4-Chlorophenyl)(1-((2,3-Dihydro-1,4-Benzodioxin-2-Yl)Methyl)-4-Piperidinyl)-, Hydrochloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing specifications such as assay, related substances, and residual solvents. We support compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.