Description

4-Methoxy-[7-13C]-Benzyl Alcohol is a stable isotope-labeled derivative of 4-methoxybenzyl alcohol, where the carbon-13 isotope is incorporated at a specific position on the aromatic ring. This precise labeling makes it an indispensable internal standard and tracer in advanced analytical chemistry, ensuring unparalleled accuracy in quantitative mass spectrometry and NMR studies. It is primarily required by pharmaceutical R&D laboratories, contract research organizations (CROs), and academic institutions engaged in drug metabolism and pharmacokinetics (DMPK) research, proteomics, and metabolic pathway analysis.

Application

• Quantitative Mass Spectrometry (MS): Serves as a critical internal standard for the precise quantification of 4-methoxybenzyl alcohol and related metabolites in complex biological matrices like plasma, urine, and tissue homogenates.
• Drug Metabolism & Pharmacokinetics (DMPK): Used as a stable isotope tracer to study the absorption, distribution, metabolism, and excretion (ADME) profiles of drug candidates and their metabolites.
• Nuclear Magnetic Resonance (NMR) Spectroscopy: Acts as a spectroscopic probe in 13C-NMR studies to elucidate molecular structures, reaction mechanisms, and dynamics in chemical and biochemical systems.
• Proteomics & Metabolomics Research: Enables accurate relative and absolute quantification in large-scale profiling studies, helping to identify biomarkers and understand disease mechanisms.
• Synthesis of Labeled Compounds: Functions as a key synthetic intermediate for preparing more complex carbon-13 labeled fine chemicals, APIs (Active Pharmaceutical Ingredients), and diagnostic agents.
• Quality Control & Method Validation: Essential for developing and validating highly accurate analytical methods in GLP (Good Laboratory Practice) and GMP (Good Manufacturing Practice) environments.

Basic Information

Product Name	4-Methoxy-[7-13C]-Benzyl Alcohol
CAS No.	76104-36-4
Molecular Formula	C8H10O2 (13C at position 7)
Molecular Weight	139.16 g/mol (for 13C labeled form)
Synonyms	(4-Methoxyphenyl)[7-13C]methanol; p-Methoxy[7-13C]benzyl Alcohol; [7-13C]-4-Methoxybenzyl Alcohol; 4-Methoxybenzyl-7-13C Alcohol; 1-(13C)Methyl-4-methoxybenzene; (4-Methoxybenzyl)-7-13C Alcohol; p-Anisyl-7-13C Alcohol; 4-Methoxybenzenemethanol-7-13C
EINECS	Contact for details

Quality Control

Our 4-Methoxy-[7-13C]-Benzyl Alcohol is manufactured under controlled conditions to ensure exceptional isotopic and chemical purity, critical for sensitive analytical applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing isotopic enrichment (typically ≥99 atom % 13C), chemical purity (by HPLC/NMR), and confirming the absence of unlabeled species. We adhere to stringent quality protocols to ensure batch-to-batch consistency and reliability for your most demanding research.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. Due to its nature as an alcohol derivative, it should be kept away from strong oxidizing agents. For long-term storage under an inert atmosphere (nitrogen or argon) is recommended to preserve stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR / NMR)	Conforms to structure
Isotopic Enrichment (13C)	≥99 atom %
Chemical Purity (HPLC)	≥98%
Isotopic Purity (by MS)	≥99% (M+1)
Water Content (KF)	≤0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.