Description

(R)-3,3'-Dibromo-2,2'-Dimethoxy-1,1'-Binaphthyl is a chiral binaphthyl derivative, a crucial building block in asymmetric synthesis and catalysis. Its value lies in its rigid, axially chiral structure, which is essential for inducing stereoselectivity in complex organic transformations. This high-purity intermediate is primarily needed by research institutions and pharmaceutical companies developing novel active pharmaceutical ingredients (APIs) and advanced materials.

Application

• Chiral Ligand Precursor: Serves as a key intermediate for synthesizing sophisticated phosphine, phosphoramidite, and N-heterocyclic carbene (NHC) ligands used in asymmetric hydrogenation and cross-coupling reactions.
• Organocatalyst Synthesis: Employed in the construction of Brønsted acid and phase-transfer catalysts for enantioselective C-C and C-X bond formation.
• Pharmaceutical Intermediate: Used in the research and development of chiral drugs, particularly in constructing complex molecular architectures with defined stereocenters.
• Material Science: Acts as a monomer or dopant for creating chiral polymers, liquid crystals, and advanced optical materials with specific helical structures.
• Analytical Chemistry: Utilized as a chiral selector or stationary phase modifier in High-Performance Liquid Chromatography (HPLC) for enantiomer separation.

Basic Information

Product Name	(R)-3,3'-Dibromo-2,2'-Dimethoxy-1,1'-Binaphthyl
CAS No.	75714-60-2
Molecular Formula	C₂₂H₁₆Br₂O₂
Molecular Weight	472.17 g/mol
Synonyms	(R)-3,3'-Dibromo-2,2'-dimethoxy-1,1'-binaphthalene; (R)-3,3'-Dibromo-2,2'-dimethoxy-1,1'-binaphthyl; (R)-3,3'-Dibromo-2,2'-dimethoxy-[1,1'-binaphthalene]; (R)-BINOL-3,3'-dibromo-2,2'-dimethyl ether; (R)-3,3'-Dibromo-2,2'-dimethoxybinaphthyl; (R)-3,3'-Dibromo-2,2'-dimethoxy-1,1'-binaphthyl; (R)-3,3'-Dibromo-2,2'-dimethoxy-[1,1']binaphthalenyl
EINECS	Contact for details

Quality Control

Our (R)-3,3'-Dibromo-2,2'-Dimethoxy-1,1'-Binaphthyl is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure compliance with exacting research and development standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and chiral excess is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.