Description

2-Fluoro-6-Methoxyphenylboronic Acid Dimethyl Ester is a high-purity, synthetically valuable organoboron reagent. This compound is essential for modern cross-coupling reactions, enabling the efficient construction of complex biaryl and heteroaryl structures. It is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries for the development of new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key building block in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly those containing fluorinated biphenyl or heterocyclic motifs.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine and methoxy substituents can enhance biological activity and environmental stability.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands and catalysts used in asymmetric synthesis and other catalytic processes.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as polymers and small molecules for OLEDs or organic photovoltaics.
• Chemical Biology Probes: Useful for constructing molecular probes and tags for studying biological systems and diagnostic applications.
• Custom Synthesis & Contract Manufacturing: A critical reagent for custom synthesis houses and CDMOs serving the life sciences sector.

Basic Information

Product Name	2-Fluoro-6-Methoxyphenylboronic Acid Dimethyl Ester
CAS No.	75626-21-0
Molecular Formula	C9H12BFO3
Molecular Weight	197.99 g/mol
Synonyms	(2-Fluoro-6-methoxyphenyl)boronic Acid Dimethyl Ester; Dimethyl (2-Fluoro-6-methoxyphenyl)boronate; 2-Fluoro-6-methoxybenzeneboronic Acid Dimethyl Ester; B-(2-Fluoro-6-methoxyphenyl)boronic Acid Dimethyl Ester; (2-Fluoro-6-methoxybenzene)boronic Acid Dimethyl Ester; 75626-21-0; 2-Fluoro-6-methoxybenzeneboronic Acid Dimethyl Ester
EINECS	Contact for details

Quality Control

Our 2-Fluoro-6-Methoxyphenylboronic Acid Dimethyl Ester is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC, to ensure high chemical purity and identity. Certificates of Analysis (COA) with lot-specific data are provided to guarantee reproducible performance in your synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage or after opening to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.