Description

Bromosulbactam CAS NO 75527-87-6 is a specialized β-lactamase inhibitor, a brominated derivative of sulbactam designed to enhance antibacterial efficacy. This compound is critical for overcoming bacterial resistance, particularly in combination therapies targeting resistant pathogens. It is primarily required by pharmaceutical R&D departments, fine chemical manufacturers, and academic research institutions focused on developing next-generation antimicrobial agents and studying resistance mechanisms.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel β-lactam antibiotic combinations.
• Antimicrobial Research: Used in biochemical and microbiological studies to investigate and combat β-lactamase-mediated antibiotic resistance.
• Combination Therapy Development: Employed in preclinical research to formulate enhanced antibiotic formulations with a broader spectrum of activity.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Biochemical Probe: Utilized in enzymatic studies to understand the inhibition kinetics and binding mechanisms of β-lactamases.

Basic Information

Product Name	Bromosulbactam
CAS No.	75527-87-6
Molecular Formula	C8H10BrNO5S
Molecular Weight	312.14 g/mol
Synonyms	(2S,5R)-3,3-Dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid 4,4-dioxide, 6-Bromo derivative; 6-Bromopenicillanic acid sulfone; 6-Bromosulbactam; Bromo-sulbactam; Penicillanic acid, 6-bromo-, 1,1-dioxide
EINECS	Contact for details

Quality Control

Our Bromosulbactam is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to cGMP guidelines where applicable to support our clients' regulatory and quality requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.