Description

(S)-2-Methyloxetane CAS NO 75492-29-4 is a high-purity, chiral oxetane building block of significant interest in advanced organic synthesis. Its strained four-membered oxetane ring and defined stereochemistry make it a valuable precursor for constructing complex molecules with precise three-dimensional architecture. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the development of active pharmaceutical ingredients (APIs), agrochemicals, and novel materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) and anti-infective agents.
• Agrochemical Synthesis: Used in the research and development of advanced, stereospecific pesticides and herbicides where the (S)-enantiomer imparts specific biological activity.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis to induce high enantioselectivity.
• Polymer Science: Employed as a monomer or co-monomer for creating specialty polymers with unique thermal or mechanical properties derived from the oxetane ring.
• Material Science Research: Investigated for developing advanced functional materials, including liquid crystals and photoactive compounds.
• Academic & Process Chemistry: A valuable reagent for methodological studies in ring-opening reactions and the construction of oxygen-containing heterocycles in academic and industrial R&D settings.

Basic Information

Product Name	(S)-2-Methyloxetane
CAS No.	75492-29-4
Molecular Formula	C4H8O
Molecular Weight	72.11 g/mol
Synonyms	(S)-2-Methyloxacyclobutane; (S)-2-Methyl-1,3-propylene oxide; (S)-(-)-2-Methyloxetane; (S)-2-Methyloxetane; (S)-2-Methyl-oxetane; (S)-Oxetane, 2-methyl-; (2S)-2-Methyloxetane; (S)-2-Methyl-oxacyclobutane
EINECS	Contact for details

Quality Control

Our (S)-2-Methyloxetane is produced under stringent quality control protocols to ensure high chemical and enantiomeric purity suitable for demanding synthetic applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles. We adhere to cGMP principles where applicable, and our quality systems are designed to meet the rigorous standards of the pharmaceutical and fine chemical industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its highly volatile nature, ensure containers are kept tightly sealed and upright. Keep away from heat, sparks, open flames, and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Enantiomeric Excess (Chiral GC/HPLC)	≥ 98.0% ee
Water Content (Karl Fischer)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.