Description

14,15-Leukotriene D4 is a specialized eicosanoid metabolite of leukotriene D4, playing a significant role in inflammatory and immunological signaling pathways. This compound is crucial for advanced biochemical research and pharmaceutical development targeting inflammatory diseases. It is primarily utilized by research institutions and pharmaceutical companies focused on respiratory and allergic conditions, cardiovascular research, and the development of leukotriene receptor antagonists.

Application

• Biochemical Research: Used as a high-purity reference standard in studies of eicosanoid metabolism and leukotriene signaling cascades.
• Pharmaceutical R&D: Serves as a critical intermediate or analytical standard in the development of anti-inflammatory drugs and leukotriene pathway inhibitors.
• In Vitro Diagnostics: Employed in the development and calibration of immunoassays and ELISA kits for detecting inflammatory biomarkers.
• Cell Biology Studies: Applied in research investigating the role of leukotrienes in cellular processes such as chemotaxis, vascular permeability, and bronchoconstriction.
• Academic Research: Utilized in university and institutional labs for fundamental research in immunology, pharmacology, and molecular biology.

Basic Information

Product Name	14,15-Leukotriene D4
CAS No.	75290-64-1
Molecular Formula	C25H40N2O7S
Molecular Weight	512.66 g/mol
Synonyms	14,15-Dihydroxy-leukotriene D4; 14,15-LTD4; 14,15-DiHETE-cysteinylglycine; (5S,6R,14R,15S)-14,15-Dihydroxy-6-[(2E)-3-[(1R,2E,4E,6Z,9Z)-1-[(carboxymethyl)amino]-2,4,6,9-hexadecatetraen-1-yl]sulfanyl]propanoyl]amino]-5-hydroxyicosa-7,9,11-trien-1-oic acid; LTD4 metabolite; Leukotriene D4 14,15-diol
EINECS	Contact for details

Quality Control

Our 14,15-Leukotriene D4 is produced under stringent quality management systems to ensure the highest standards of purity and batch-to-batch consistency, suitable for sensitive research applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant guidelines for research-grade biochemicals to guarantee reliability for your critical experiments.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below. The product is light-sensitive and should be handled under appropriate conditions to prevent degradation. Allow the vial to reach room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Solubility	Soluble in ethanol, DMSO; slightly soluble in aqueous buffer

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.