Description

α-Ketokainic Acid is a specialized kainate receptor agonist and a key chemical intermediate in neuroscience and pharmaceutical research. This compound is valued for its role in studying excitatory neurotransmission and glutamate receptor function. It is primarily utilized by research institutions and pharmaceutical companies engaged in neuropharmacology, neurotoxicology, and the development of treatments for neurological disorders.

Application

• Neuroscience Research: As a potent agonist for kainate receptors, it is a critical tool for studying excitatory amino acid pathways, synaptic plasticity, and neuronal excitotoxicity.
• Pharmacological Studies: Used in the screening and development of novel neuroprotective agents or glutamate receptor modulators for conditions like epilepsy, stroke, and neurodegenerative diseases.
• Biochemical Standard: Serves as a high-purity reference standard in analytical laboratories for method development and quality control of related compounds.
• Chemical Synthesis: Acts as a sophisticated building block or intermediate in the synthesis of more complex neuroactive molecules and labeled analogs for tracer studies.

Basic Information

Product Name	α-Ketokainic Acid
CAS No.	75232-58-5
Molecular Formula	C10H11NO5
Molecular Weight	225.20 g/mol
Synonyms	α-Ketokainic Acid; 3-Carboxy-4-(1-carboxyethenyl)-3-pyrroline-2-acetic Acid; 2-(2-Carboxy-3-carboxymethyl-4-isopropenyl)pyrrolidine-3-carboxylic Acid; Kainic Acid Ketone Derivative; (2S,3S,4S)-3-Carboxy-4-(prop-1-en-2-yl)pyrrolidine-2,5-dicarboxylic acid 2,5-dione (related IUPAC forms)
EINECS	Contact for details

Quality Control

Our α-Ketokainic Acid is produced and tested under a strict quality management system. Each batch is analyzed to ensure high chemical purity and identity, meeting the exacting standards required for research applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The container should be kept in a well-ventilated area and protected from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Assay	≥ 97.0%
Water Content	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.