Description

Benzoquinone, [14C(U)] is a carbon-14 radiolabeled analog of 1,4-benzoquinone, a fundamental quinone compound. This isotopically labeled material is essential for conducting detailed metabolic, environmental, and pharmacokinetic studies where precise tracking of the benzoquinone moiety is required. It is a critical tool for researchers and scientists in the pharmaceutical, agrochemical, and environmental safety sectors who require definitive data on compound fate, degradation pathways, and metabolite identification.

Application

• Tracer Studies in Metabolism Research: Used to elucidate the metabolic pathways and biotransformation of benzoquinone and related compounds in biological systems.
• Environmental Fate and Degradation Analysis: Employed to track the environmental persistence, breakdown products, and transport of quinone-based chemicals in soil and water studies.
• Drug Metabolism and Pharmacokinetics (DMPK): Serves as a key radiolabeled intermediate in the development and regulatory submission of new pharmaceutical entities, enabling mass balance studies.
• Mechanistic Biochemical Research: Facilitates investigations into redox cycling, oxidative stress mechanisms, and protein binding where the benzoquinone structure plays a role.
• Agrochemical Research: Applied in studies to understand the mode of action, metabolism, and residue analysis of quinone-containing pesticides or herbicides.
• Synthesis of Labeled Complex Molecules: Acts as a building block for the synthesis of more complex carbon-14 labeled compounds for advanced research applications.

Basic Information

Product Name	Benzoquinone, [14C(U)]
CAS No.	75221-31-7
Molecular Formula	C6H414CO2
Molecular Weight	~110.1 g/mol (specific activity dependent)
Synonyms	1,4-Benzoquinone-[14C(U)]; p-Benzoquinone-[ring-U-14C]; [U-14C]-1,4-Benzoquinone; 2,5-Cyclohexadiene-1,4-dione-[14C(U)]; Carbon-14 Labeled Benzoquinone; Radiolabeled p-Quinone; [14C]BQ
EINECS	Contact for details

Quality Control

Every batch of Benzoquinone, [14C(U)] is manufactured and analyzed under strict quality systems to ensure identity, purity, and specific activity. Comprehensive analytical control includes techniques such as radio-HPLC and radio-TLC to confirm radiochemical purity and chemical purity. A detailed Certificate of Analysis (COA) is provided with each shipment, specifying batch-specific data including specific activity (mCi/mmol or GBq/mmol), concentration, solvent, and analytical results.

Storage

Preserve in a tightly closed container, protected from light. Store at the recommended temperature as specified on the label or COA, typically between 2°C and 8°C for many radiolabeled compounds. This product is highly volatile and should be handled with appropriate care in a controlled environment to prevent loss and ensure safety. Always refer to the material-specific safety data sheet for complete handling and storage instructions.

Specification

Item	Specification
Appearance	Solution (color as per specific batch)
Identification (HPLC, TLC)	Conforms to reference standard
Chemical Purity (HPLC)	≥ 98%
Radiochemical Purity	≥ 97%
Specific Activity	Customized (mCi/mmol or GBq/mmol)
Concentration	Customized (mCi/mL or MBq/mL)
Solvent	As specified (e.g., Toluene, Acetonitrile)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.