Description

Methyl (S)-(-)-1-Trityl-2-Aziridine is a high-value, chiral aziridine derivative used as a key synthetic intermediate in advanced organic chemistry. This compound matters for its role in constructing complex, stereodefined molecules, particularly in the synthesis of pharmaceuticals and bioactive compounds. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the development of new active ingredients and chiral ligands.

Application

• Pharmaceutical Intermediate: A crucial chiral building block for the synthesis of novel active pharmaceutical ingredients (APIs), especially those containing nitrogen heterocycles.
• Asymmetric Synthesis: Employed as a chiral auxiliary or reagent in stereoselective reactions to introduce nitrogen-containing stereocenters with high enantiomeric purity.
• Agrochemical Research: Used in the development of new, more effective herbicides, fungicides, and insecticides with specific chiral configurations.
• Ligand and Catalyst Preparation: Serves as a precursor for the synthesis of chiral ligands and organocatalysts used in transition metal catalysis and enantioselective transformations.
• Academic & R&D Laboratories: A valuable tool for methodological development in organic synthesis and for exploring new reaction pathways involving strained three-membered rings.
• Fine Chemical Production: Used in the custom synthesis of complex, high-value specialty chemicals for various technological applications.

Basic Information

Product Name	Methyl (S)-(-)-1-Trityl-2-Aziridine
CAS No.	75154-68-6
Molecular Formula	C22H21N
Molecular Weight	299.41 g/mol
Synonyms	(S)-1-Trityl-2-methylaziridine; (S)-(-)-1-Trityl-2-methylaziridine; (S)-1-Triphenylmethyl-2-methylaziridine; Methyl (S)-(-)-1-tritylaziridine; (2S)-1-Trityl-2-methylaziridine; 1-Trityl-2-methyl-(S)-aziridine; Aziridine, 1-(triphenylmethyl)-2-methyl-, (2S)-
EINECS	Contact for details

Quality Control

Every batch of Methyl (S)-(-)-1-Trityl-2-Aziridine is produced and tested under strict quality management protocols to ensure identity, purity, and chiral integrity. Our standard quality commitment includes comprehensive analysis via HPLC, NMR, and optical rotation measurement. A Certificate of Analysis (COA) detailing purity, enantiomeric excess, and other critical parameters is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept tightly sealed in a dry environment to prevent moisture uptake, which can affect stability and performance. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	Contact for details
Specific Rotation [α]	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.