Description

25-Hydroxy-24-Oxocholecalciferol is a key metabolite and synthetic intermediate in the vitamin D pathway. This compound is of significant value for research and development in the pharmaceutical and nutraceutical industries, particularly for studying vitamin D metabolism and synthesizing advanced analogs. It is primarily needed by manufacturers of active pharmaceutical ingredients (APIs), research institutions, and companies developing therapeutic agents for bone health, immune modulation, and endocrine disorders.

Application

• Pharmaceutical Intermediate: Critical precursor in the synthesis of advanced vitamin D analogs and active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a reference standard and tool compound for studying vitamin D metabolism, receptor binding, and enzymatic pathways.
• Nutraceutical Development: Serves in the R&D of novel dietary supplements targeting calcium homeostasis and bone health.
• Metabolite Standard: Essential for analytical method development and validation in clinical and preclinical studies for accurate quantification.
• Endocrinology Studies: Applied in research focused on the endocrine functions of vitamin D and its role in cellular regulation.

Basic Information

Product Name	25-Hydroxy-24-Oxocholecalciferol
CAS No.	74886-61-6
Molecular Formula	C₂₇H₄₂O₃
Molecular Weight	414.62 g/mol
Synonyms	24-Oxo-25-hydroxyvitamin D3; 24-Oxocalcidiol; (5Z,7E)-9,10-Secocholesta-5,7,10(19)-triene-3β,25-diol-24-one; 25-Hydroxy-24-oxovitamin D3; 24-Keto-25-hydroxyvitamin D3; 24-Oxo-25-hydroxycholecalciferol
EINECS	Contact for details

Quality Control

Our 25-Hydroxy-24-Oxocholecalciferol is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets high-purity standards suitable for research and pharmaceutical applications. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and analytical methods is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and light-sensitive; ensure the container is sealed under an inert atmosphere after each use to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.