Description

Methyl[Methyl(1-Methylethyl)Cyclohexyl]Phenylphosphine is a specialized organophosphorus compound characterized by its sterically demanding, electron-rich phosphine ligand structure. This compound matters as a highly effective ligand in homogeneous catalysis, particularly for facilitating challenging cross-coupling and hydrogenation reactions due to its ability to stabilize reactive metal centers. It is primarily needed by R&D chemists and process engineers in the pharmaceutical, agrochemical, and advanced materials sectors for developing novel synthetic pathways and optimizing industrial catalytic processes.

Application

• As a key ligand in palladium-catalyzed cross-coupling reactions (e.g., Suzuki-Miyaura, Buchwald-Hartwig amination) for pharmaceutical intermediate synthesis.
• Employed in asymmetric hydrogenation and hydroformylation catalysts for the production of chiral active pharmaceutical ingredients (APIs).
• Utilized in olefin polymerization and oligomerization catalysts for creating specialty polymers with tailored properties.
• Serves as a precursor for synthesizing advanced phosphonium salts and ionic liquids used in specialty chemical applications.
• Applied in academic and industrial research for developing new catalytic systems and exploring novel reaction mechanisms.
• Used in the fine chemical industry for the scalable synthesis of complex organic molecules where traditional ligands fail.

Basic Information

Product Name	Methyl[Methyl(1-Methylethyl)Cyclohexyl]Phenylphosphine
CAS No.	74709-99-2
Molecular Formula	C17H27P
Molecular Weight	262.37 g/mol
Synonyms	Methyl(isopropylcyclohexyl)phenylphosphine; (Cyclohexyl(isopropyl)methyl)phenylphosphine; Methyl(1-methylethyl)cyclohexylphenylphosphine; (1-Methylethyl)cyclohexyl(methyl)phenylphosphine; Tertiary phosphine ligand 74709-99-2; P,C-Ligand; Sterically hindered phosphine; Isopropylcyclohexylmethylphenylphosphine
EINECS	Contact for details

Quality Control

Our Methyl[Methyl(1-Methylethyl)Cyclohexyl]Phenylphosphine is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including NMR (1H, 13C, 31P) and GC/HPLC analysis, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment ensures material consistency critical for reproducible catalytic performance in your applications.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) in a cool, dry, and well-ventilated place. Recommended storage temperature is 2-8°C for long-term stability. Due to its sensitivity to oxidation, containers should be purged with inert gas after each opening.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (NMR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.