Description

2-Oxo-3β-(2-Phenylacetamido)-4β-Mercaptoazetidine is a specialized β-lactam derivative, a key structural motif in advanced pharmaceutical synthesis. This compound matters as a versatile chiral building block and synthetic intermediate, offering a unique scaffold for developing novel active pharmaceutical ingredients (APIs). It is primarily needed by research institutions and manufacturers in the pharmaceutical and fine chemical industries for the development of new therapeutic agents, particularly in antibiotic and enzyme inhibitor research.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the research and development of novel β-lactam antibiotics and other therapeutic compounds.
• Organic Synthesis Building Block: Utilized in complex multi-step syntheses to introduce the azetidinone ring system with defined stereochemistry.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies in drug discovery programs targeting bacterial enzymes.
• Process Chemistry Development: Used in route scouting and optimization for the scalable production of target drug candidates.
• Academic & Industrial R&D: Employed in chemical biology and biochemical studies as a potential enzyme inhibitor or probe molecule.

Basic Information

Product Name	2-Oxo-3β-(2-Phenylacetamido)-4β-Mercaptoazetidine
CAS No.	74643-21-3
Molecular Formula	C11H12N2O2S
Molecular Weight	236.29 g/mol
Synonyms	3β-(2-Phenylacetamido)-4β-mercaptoazetidin-2-one; 4β-Mercapto-3β-(phenylacetamido)azetidin-2-one; (3R,4R)-3-[(2-Phenylacetyl)amino]-4-mercaptoazetidin-2-one; β-Lactam intermediate; Azetidinone derivative; Thioazetidinone; Phenylacetamido mercaptoazetidinone
EINECS	Contact for details

Quality Control

Our 2-Oxo-3β-(2-Phenylacetamido)-4β-Mercaptoazetidine is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral integrity, to ensure it meets the high standards required for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment. For long-term storage, consider storing under an inert atmosphere (e.g., nitrogen or argon) to minimize potential oxidation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.