Description

Pyrraline CAS NO 74509-14-1 is an advanced glycation end-product (AGE) derived from the Maillard reaction, serving as a critical biomarker for oxidative stress and protein glycation. Its significance lies in its role as a key research tool for studying metabolic disorders, aging processes, and diabetic complications. This compound is essential for researchers and manufacturers in the fields of biochemical research, diagnostic assay development, and pharmaceutical R&D.

Application

• Biochemical Research Standard: Used as a reference standard in studies of non-enzymatic glycation and the formation of advanced glycation end-products (AGEs).
• Diagnostic Development: A key antigen for developing immunoassays (ELISA) to detect AGE levels in biological samples for clinical research.
• Metabolic Disease Studies: Critical for investigating the pathophysiology of diabetes, aging, and related complications like neuropathy and nephropathy.
• Pharmaceutical Screening: Employed in high-throughput screening assays to identify potential therapeutic agents that inhibit AGE formation.
• Food Science Research: Used to study the Maillard reaction in food processing and its implications for nutrition and food safety.
• Academic & Institutional Labs: Serves as a vital reagent for universities and research institutes focusing on biochemistry and molecular biology.

Basic Information

Product Name	Pyrraline
CAS No.	74509-14-1
Molecular Formula	C8H11NO4
Molecular Weight	185.18 g/mol
Synonyms	1-(5-Amino-5-carboxypentyl)-2-formyl-3,4-dihydro-5-hydroxypyridinium inner salt; 1-(5-Amino-5-carboxypentyl)-5-hydroxy-2-formyl-3,4-dihydropyridinium inner salt; 1-(5-Amino-5-carboxypentyl)-5-hydroxy-2-formyl-3,4-dihydropyridinium hydroxide inner salt; 2-Formyl-5-hydroxy-methylpyridinium lysine; AGE Pyrraline; N(6)-(2-Formyl-5-hydroxy-methylpyridinium-1-yl)-L-lysine inner salt; Pyrraline (AGE)
EINECS	Contact for details

Quality Control

Our Pyrraline is produced under strict quality management protocols to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to ISO 9001 standards, and our quality systems support compliance for research use in regulated environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term stability, consider storage under inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.