Description

(2R,3S)-3-Methylpent-4-En-2-Ol CAS NO 74080-51-6 is a high-purity chiral alcohol building block characterized by its specific stereochemistry at the 2 and 3 positions. This compound is a valuable intermediate in asymmetric synthesis, enabling the production of enantiomerically pure pharmaceuticals and fine chemicals. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and advanced material sectors for the development of novel active ingredients and specialty polymers.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs), particularly in antiviral and cardiovascular drug research.
• Agrochemical Synthesis: Used in the production of chiral pesticides and herbicides, where specific stereochemistry is crucial for biological activity and environmental safety.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric hydrogenation and carbon-carbon bond-forming reactions.
• Flavor and Fragrance Industry: Employed in the synthesis of complex, natural-identical aroma chemicals requiring specific stereoisomers for authentic scent profiles.
• Material Science: Acts as a monomer or cross-linking agent in the development of specialized polymers with tailored optical or mechanical properties.
• Academic and R&D: A critical reagent for methodological studies in organic chemistry and for exploring new synthetic pathways in laboratory settings.

Basic Information

Product Name	(2R,3S)-3-Methylpent-4-En-2-Ol
CAS No.	74080-51-6
Molecular Formula	C6H12O
Molecular Weight	100.16 g/mol
Synonyms	(2R,3S)-3-Methyl-4-penten-2-ol; (2R,3S)-3-Methylpent-4-en-2-ol; 3-Methyl-4-penten-2-ol, (2R,3S)-; (2R,3S)-3-Methyl-1-buten-3-ol (tautomer); 4-Penten-2-ol, 3-methyl-, (2R,3S)-; Chiral 3-Methylpent-4-en-2-ol; (R,S)-3-Methylpent-4-en-2-ol (relative configuration)
EINECS	Contact for details

Quality Control

Our (2R,3S)-3-Methylpent-4-En-2-Ol is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by GC or HPLC, to ensure high enantiomeric excess (ee) and chemical purity. Certificates of Analysis (COA) detailing identity, assay, impurity profile, and specific rotation are available upon request. We support development and cGMP-grade production for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flames. For long-term storage under an inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0% ee
Specific Rotation	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.