Description

Enfuvirtide is a synthetic peptide drug substance, a potent and selective inhibitor of HIV-1 fusion with host cells. This compound is critical for the formulation of antiretroviral therapies targeting treatment-experienced patients or those with multi-drug resistant HIV-1 strains. It is primarily utilized by pharmaceutical manufacturers and research institutions in the development and production of advanced HIV therapeutics.

Application

• Active Pharmaceutical Ingredient (API) for injectable antiretroviral drugs.
• Research & Development of novel HIV fusion inhibitor therapies.
• Reference Standard for analytical method development and quality control in pharmaceutical laboratories.
• Formulation Studies for stability testing and dosage form optimization.
• Pre-clinical and Clinical Trial Material for investigative new drug applications.

Basic Information

Product Name	Enfuvirtide
CAS No.	74038-65-6
Molecular Formula	C204H301N51O64
Molecular Weight	4491.9 g/mol
Synonyms	T-20; DP-178; Pentafuside; Fuzeon (Brand Name); HIV-1 Fusion Inhibitor T-20; Enfuvirtide Acetate; N-Acetyl-Tyr-Thr-Ser-Leu-Ile-His-Ser-Leu-Ile-Glu-Glu-Ser-Gln-Asn-Gln-Gln-Glu-Lys-Asn-Glu-Gln-Glu-Leu-Leu-Glu-Leu-Asp-Lys-Trp-Ala-Ser-Leu-Trp-Asn-Trp-Phe-NH2
EINECS	Contact for details

Quality Control

Our Enfuvirtide is manufactured under strict quality systems. Each batch is tested to ensure it meets high-purity standards suitable for pharmaceutical applications, with specifications aligned with pharmacopeial guidelines. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to ensure traceability and regulatory compliance.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as specified on the label. This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Individual impurity: ≤ 1.0% Total impurities: ≤ 2.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Bacterial Endotoxins	< 1.0 EU/mg
Microbial Enumeration	Meets Ph. Eur. 2.6.12/ USP <61>

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.