Description

Atropine Sulfate is a high-purity, crystalline salt of the tropane alkaloid atropine, widely recognized for its potent anticholinergic and antimuscarinic properties. This compound is critical for its role as a pre-anesthetic agent to inhibit salivation and bronchial secretions, and as an antidote for organophosphate and carbamate poisoning. It serves as an essential active pharmaceutical ingredient (API) and research chemical for the pharmaceutical, biotechnology, and life science research sectors globally. Consistent quality and reliable supply are paramount for its use in critical medical and diagnostic applications.

Application

• Pharmaceutical Manufacturing: Primary use as an Active Pharmaceutical Ingredient (API) in injectable formulations, ophthalmic solutions, and pre-operative medications.
• Emergency Medicine: Critical component in auto-injectors and emergency kits as an antidote for nerve agent and pesticide (organophosphate/carbamate) poisoning.
• Ophthalmic Procedures: Used in eye drops to induce mydriasis (pupil dilation) and cycloplegia (paralysis of accommodation) for diagnostic examinations and surgery.
• Anesthesiology: Administered pre-operatively to reduce airway secretions and prevent bradycardia during surgery.
• Cardiology: Employed in specific protocols for treating symptomatic bradycardia (slow heart rate).
• Veterinary Medicine: Used in veterinary practices for similar therapeutic purposes as in human medicine.
• Biochemical Research: Valuable tool in pharmacological studies and receptor binding assays targeting muscarinic acetylcholine receptors.
• Reference Standard: Serves as a high-purity chemical standard for quality control and analytical testing in laboratories.

Basic Information

Product Name	Atropine Sulfate
CAS No.	73791-47-6
Molecular Formula	C34H48N2O10S
Molecular Weight	676.82 g/mol
Synonyms	Atropine Sulphate; Atropine Sulfate Salt; Atropinium Sulfate; dl-Hyoscyamine Sulfate; (±)-Hyoscyamine Sulfate; 8-Methyl-8-azabicyclo[3.2.1]oct-3-yl 3-hydroxy-2-phenylpropanoate sulfate (1:1); Tropine tropate sulfate; Endopsychosin Sulfate
EINECS	Contact for details

Quality Control

Our Atropine Sulfate is manufactured under strict quality systems to ensure it meets the stringent requirements of pharmaceutical applications. Each batch is tested against relevant pharmacopoeial standards (such as USP, EP, or BP) for identity, purity, and potency. Comprehensive testing includes assay, related substances, residual solvents, and microbiological examination. A Certificate of Analysis (COA) documenting all test results is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent absorption of atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White or almost white, crystalline powder
Identification (IR)	Conforms to standard
Identification (TLC)	Conforms to standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
pH (5% solution)	4.5 - 6.0
Specific Rotation	-0.30° to +0.30°
Related Substances (HPLC)	Total impurities ≤ 2.0% Any individual impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C
Water (KF)	≤ 5.0%
Sulfated Ash	≤ 0.1%
Heavy Metals	≤ 20 ppm
Microbial Limits	Complies with Ph. Eur. 2.6.12/2.6.13

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.