Description

Alpha,α-Difluoro-1-Naphthaleneacetic Acid is a specialized fluorinated derivative of naphthaleneacetic acid, a compound class known for its biological activity. This product is valued for its role as a key synthetic intermediate in the development of advanced agrochemicals and pharmaceuticals, where the introduction of fluorine atoms can significantly alter biological activity and metabolic stability. It is primarily sought by research institutions and industrial manufacturers in the agrochemical and pharmaceutical sectors for the synthesis of novel active ingredients.

Application

• Agrochemical Intermediate: A key building block for the synthesis of novel herbicides, plant growth regulators, and fungicides, leveraging the bioactivity of the naphthaleneacetic acid core.
• Pharmaceutical Research: Used in medicinal chemistry as a precursor for developing potential drug candidates, particularly where fluorination is used to optimize pharmacokinetic properties.
• Chemical Synthesis: Serves as a versatile fluorinated synthon in organic chemistry for constructing complex molecules in academic and industrial R&D settings.
• Biochemical Research: Employed in studies investigating auxin-like activity and plant hormone signaling pathways due to its structural relationship to naphthaleneacetic acid.

Basic Information

Product Name	Alpha,α-Difluoro-1-Naphthaleneacetic Acid
CAS No.	73790-14-4
Molecular Formula	C₁₂H₈F₂O₂
Molecular Weight	222.19 g/mol
Synonyms	2-(Naphthalen-1-yl)-2,2-difluoroacetic Acid; 1-Naphthaleneacetic Acid, α,α-Difluoro-; Difluoronaphthaleneacetic Acid; α,α-Difluoro-1-naphthylacetic Acid; 2,2-Difluoro-2-(1-naphthyl)acetic Acid; NAA Difluoro Derivative; (1-Naphthyl)difluoroacetic Acid
EINECS	Contact for details

Quality Control

Our Alpha,α-Difluoro-1-Naphthaleneacetic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with key parameters including assay, impurity profile, and physical characterization. Our quality commitment ensures the material meets the stringent requirements for research and scale-up synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area. For long-term storage, maintaining the product at 2-8°C (refrigerated) is recommended to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.