Description

3-Deoxy-18-Hydroxyryanodol is a high-purity, structurally defined ryanodane diterpenoid derivative. This compound serves as a critical reference standard and advanced intermediate in pharmaceutical research and development, particularly in the study of calcium channel modulation. It is essential for researchers and manufacturers in the life sciences sector requiring precise chemical tools for mechanistic studies and analytical method validation. The product is supplied with full analytical documentation to ensure traceability and reliability for your most demanding applications.

Application

• Pharmaceutical Reference Standard: Used for the qualitative and quantitative analysis of ryanodane-related compounds in drug discovery and quality control laboratories.
• Calcium Signaling Research: Acts as a key biochemical tool for investigating ryanodine receptor (RyR) function and intracellular calcium release mechanisms.
• Advanced Synthetic Intermediate: Employed in the multi-step synthesis of novel bioactive molecules and complex natural product analogs.
• Analytical Method Development: Serves as a calibration standard for developing and validating HPLC, LC-MS, and other chromatographic assays.
• Toxicological Studies: Utilized in research to understand the structure-activity relationships and metabolic pathways of ryanodane diterpenoids.

Basic Information

Product Name	3-Deoxy-18-Hydroxyryanodol
CAS No.	73599-13-0
Molecular Formula	C₂₀H₃₂O₇
Molecular Weight	384.47 g/mol
Synonyms	18-Hydroxy-3-deoxyryanodol; 3-Deoxy-18-hydroxyryanodol; Ryanodol, 3-deoxy-18-hydroxy-; (1R,2R,3S,6S,7S,8R,9S,10R,11S,12S,14S,16R,17R)-6,7,14,16,17-Pentahydroxy-11-methyl-13,15-dioxapentacyclo[9.3.3.12,7.19,14.01,3]heptadecan-10-ol
EINECS	Contact for details

Quality Control

Every batch of 3-Deoxy-18-Hydroxyryanodol is manufactured and tested under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure compliance with research-grade standards. A comprehensive Certificate of Analysis (COA), detailing batch-specific results, is provided with each shipment to guarantee traceability and consistency for your critical research applications.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term storage, consider storing under inert atmosphere at -20°C.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.