Description

Xamoterol Hemifumarate is a selective β-1 adrenergic receptor partial agonist, primarily recognized for its pharmacological activity. This compound is of significant interest in the research and development of cardiovascular therapeutics due to its unique inotropic effects. It serves as a critical intermediate and reference standard for pharmaceutical manufacturers, academic research institutions, and analytical laboratories focused on cardiology and receptor pharmacology.

Application

• Pharmaceutical Reference Standard: Used as a high-purity certified standard for quality control and analytical method development in drug manufacturing.
• Active Pharmaceutical Ingredient (API) Intermediate: Serves as a key synthetic precursor in the production of specialized cardiovascular drugs.
• Biochemical Research: Employed in in vitro and in vivo studies to investigate β-1 adrenergic receptor function and cardiac physiology.
• Pharmacology Studies: Utilized to explore partial agonist activity and its effects on heart rate and contractility in experimental models.
• Analytical Testing: Acts as a critical component in the calibration of HPLC, LC-MS, and other chromatographic systems for compound identification and quantification.

Basic Information

Product Name	Xamoterol Hemifumarate
CAS No.	73210-73-8
Molecular Formula	C20H30N2O9
Molecular Weight	466.46 g/mol
Synonyms	Xamoterol Fumarate (1:1); Xamoterol Hydrogen Fumarate; Corwin; ICI 118587; (RS)-N-[2-Hydroxy-3-(4-hydroxyphenoxy)propyl]-N'-phenylethylenediamine Hemifumarate; (±)-Xamoterol Hemifumarate; 1-(4-Hydroxyphenoxy)-3-[[2-(2-phenylethylamino)ethyl]amino]-2-propanol Hemifumarate
EINECS	Contact for details

Quality Control

Our Xamoterol Hemifumarate is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including identity confirmation, purity assay, and impurity profiling, to ensure it meets stringent specifications for research and pharmaceutical use. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Total impurities ≤2.0% Any single impurity ≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.