Description

Benzenemethanol, 4-Nitro-α-(Trifluoromethyl)-, (S)- (9Ci) is a high-value, single-enantiomer chiral building block characterized by its nitro and trifluoromethyl functional groups. This compound is essential for the synthesis of advanced pharmaceutical intermediates and agrochemicals, where its specific stereochemistry and fluorine content are critical for bioactivity and metabolic stability. It is primarily sought after by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in areas requiring fluorinated compounds.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides where the trifluoromethyl group enhances efficacy and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of specialty polymers and advanced organic materials with unique electronic properties.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes for studying biological systems and enzyme mechanisms.

Basic Information

Product Name	Benzenemethanol, 4-Nitro-α-(Trifluoromethyl)-, (S)- (9Ci)
CAS No.	73048-49-4
Molecular Formula	C9H6F3NO3
Molecular Weight	233.14 g/mol
Synonyms	(S)-α-(Trifluoromethyl)-4-nitrobenzenemethanol; (S)-1-(4-Nitrophenyl)-2,2,2-trifluoroethanol; (S)-4-Nitro-α-(trifluoromethyl)benzyl alcohol; (S)-2,2,2-Trifluoro-1-(4-nitrophenyl)ethanol; 73048-49-4; (S)-1-(4-Nitrophenyl)-2,2,2-trifluoroethan-1-ol; p-Nitro-α-(trifluoromethyl)benzyl alcohol, (S)-
EINECS	Contact for details

Quality Control

Our production of Benzenemethanol, 4-Nitro-α-(Trifluoromethyl)-, (S)- (9Ci) adheres to stringent quality management protocols to ensure batch-to-batch consistency and high enantiomeric purity. All materials are supported by a comprehensive Certificate of Analysis (COA) detailing purity, chiral purity (enantiomeric excess), and impurity profiles, typically determined by HPLC, GC, and chiral analysis methods. We operate in compliance with cGMP principles where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (ee)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.