Description

(S)-Tetrahydro-2H-Pyran-3-Ol is a high-purity chiral building block and intermediate of significant importance in advanced organic synthesis. Its defined stereochemistry and functionalized pyran ring structure make it a valuable precursor for the development of pharmaceuticals and fine chemicals. This compound is essential for research and production chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce chiral complexity into target molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in antiviral, cardiovascular, and central nervous system (CNS) drug candidates.
• Asymmetric Synthesis: Used as a starting material or auxiliary in catalytic asymmetric reactions to construct complex, enantiomerically pure molecules.
• Ligand and Catalyst Development: Serves as a precursor for novel chiral ligands and organocatalysts used in enantioselective transformations.
• Agrochemical Research: Employed in the synthesis of chiral herbicides, fungicides, and plant growth regulators with enhanced efficacy and selectivity.
• Flavor and Fragrance Industry: Potential intermediate for creating stereochemically defined aroma chemicals and flavorants.
• Material Science: Building block for chiral polymers or liquid crystals with specific optical properties.

Basic Information

Product Name	(S)-Tetrahydro-2H-Pyran-3-Ol
CAS No.	72886-97-6
Molecular Formula	C5H10O2
Molecular Weight	102.13 g/mol
Synonyms	(S)-3-Hydroxytetrahydro-2H-pyran; (S)-Tetrahydro-2H-pyran-3-ol; (3S)-Oxan-3-ol; (S)-3-Hydroxytetrahydropyran; (S)-3-Pyranol; (S)-3-Hydroxy-3,4,5,6-tetrahydro-2H-pyran; (S)-THP-3-ol; (S)-3-Hydroxyoxane
EINECS	Contact for details

Quality Control

Our (S)-Tetrahydro-2H-Pyran-3-Ol is produced under strict quality management systems. Each batch is characterized and tested to ensure high chemical and enantiomeric purity, meeting the stringent requirements of advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity (by GC/HPLC), chiral purity (by Chiral HPLC), and residual solvent levels is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.