Description

n-Ethyldeoxynojirimycinhcl CAS NO 72458-42-5 is a chemically modified derivative of deoxynojirimycin (DNJ), functioning as a potent and selective α-glucosidase inhibitor. This compound is of significant interest for its role in carbohydrate metabolism research and therapeutic development. It is primarily utilized by pharmaceutical R&D teams, academic researchers, and manufacturers of active pharmaceutical ingredients (APIs) focused on metabolic disorders and antiviral applications.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of more complex glycosidase inhibitors and antiviral agents.
• Biochemical Research: A critical tool compound for studying enzyme kinetics, carbohydrate processing, and glycobiology pathways in vitro.
• Metabolic Disorder Studies: Investigated for potential applications in diabetes research due to its ability to modulate blood glucose levels.
• Antiviral Agent Development: Explored for activity against viruses like HIV and hepatitis, which utilize host glycosylation machinery.
• Quality Control Standard: Serves as a reference standard in analytical laboratories for method development and validation.

Basic Information

Product Name	n-Ethyldeoxynojirimycinhcl
CAS No.	72458-42-5
Molecular Formula	C9H18N2O4 • HCl
Molecular Weight	254.71 g/mol
Synonyms	N-Ethyl-1,5-dideoxy-1,5-imino-D-glucitol hydrochloride; N-Ethyl-DNJ HCl; N-Ethyl-1-deoxynojirimycin hydrochloride; 1,5-Dideoxy-1,5-imino-N-ethyl-D-glucitol hydrochloride; N-Ethyl-1,5-imino-1,5-dideoxy-D-glucitol HCl; EDNJ HCl; (2R,3R,4R,5S)-2-(Hydroxymethyl)-1-ethyl-3,4,5-piperidinetriol hydrochloride
EINECS	Contact for details

Quality Control

Our n-Ethyldeoxynojirimycinhcl is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR, and residual solvent analysis, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with full traceability are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption and decomposition. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.