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Methyl 2-Fluoro-6-Hydroxybenzoate CAS NO 72373-81-0


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CAS No.:72373-81-0

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Methyl 2-Fluoro-6-Hydroxybenzoate is a versatile fluorinated aromatic ester that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both a fluorine atom and a phenolic hydroxyl group, makes it a valuable intermediate for creating complex molecules with tailored properties. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries seeking to develop new active ingredients and fine chemicals.

Application

  • Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in fluorinated drug candidates.
  • Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides where the fluorine atom enhances biological activity and stability.
  • Liquid Crystal Materials: Serves as a precursor in the synthesis of fluorinated liquid crystals for display technologies.
  • Polymer Chemistry: Acts as a monomer or modifying agent for creating specialty polymers with specific thermal or chemical resistance.
  • Organic Synthesis Building Block: Employed in cross-coupling reactions, esterifications, and etherifications to introduce the 2-fluoro-6-hydroxybenzoate moiety.
  • Dye and Pigment Intermediate: Utilized in the synthesis of specialized fluorinated dyes and pigments.

Basic Information

Product Name Methyl 2-Fluoro-6-Hydroxybenzoate
CAS No. 72373-81-0
Molecular Formula C8H7FO3
Molecular Weight 170.14 g/mol
Synonyms 2-Fluoro-6-hydroxybenzoic acid methyl ester; Methyl 2-fluoro-6-hydroxybenzoate; Methyl 6-hydroxy-2-fluorobenzoate; 2-Fluoro-6-methoxycarbonylphenol; Benzoic acid, 2-fluoro-6-hydroxy-, methyl ester; 72373-81-0
EINECS Contact for details

Quality Control

Our Methyl 2-Fluoro-6-Hydroxybenzoate is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) are provided with every shipment, detailing specifications for identity, assay, and impurity profiles. We support compliance with cGMP and ICH guidelines for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be stored away from direct light exposure.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Assay (HPLC) ≥98.0%
Melting Point Contact for details
Loss on Drying ≤0.5%
Residue on Ignition ≤0.1%
Related Substances (HPLC) Individual impurity ≤0.5%; Total impurities ≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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