Description

3-[4-(Trifluoromethyl)Phenoxy]Benzoic Acid is a high-value fluorinated aromatic compound that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring a trifluoromethylphenoxy group, imparts desirable properties such as enhanced lipophilicity and metabolic stability to target molecules. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the trifluoromethyl group improves biological activity and environmental persistence.
• Liquid Crystal Materials: Serves as a core component or side-chain modifier in the production of fluorinated liquid crystals for advanced display technologies.
• Polymer Chemistry: Acts as a monomer or additive to create specialty polymers with enhanced chemical resistance, thermal stability, and unique surface properties.
• Organic Electronic Materials: Investigated for use in organic light-emitting diodes (OLEDs) and semiconductor materials due to its electron-withdrawing characteristics.
• Chemical Research & Development: A versatile scaffold for medicinal chemistry and material science research, enabling structure-activity relationship (SAR) studies.

Basic Information

Product Name	3-[4-(Trifluoromethyl)Phenoxy]Benzoic Acid
CAS No.	72178-29-1
Molecular Formula	C14H9F3O3
Molecular Weight	282.21 g/mol
Synonyms	3-[4-(Trifluoromethyl)phenoxy]benzoic acid; Benzoic acid, 3-[4-(trifluoromethyl)phenoxy]-; 3-(4-Trifluoromethylphenoxy)benzoic acid; 3-(p-Trifluoromethylphenoxy)benzoic acid; 4-Trifluoromethylphenyl 3-carboxyphenyl ether; [4-(Trifluoromethyl)phenoxy]-3-benzoic acid
EINECS	Contact for details

Quality Control

Our production of 3-[4-(Trifluoromethyl)Phenoxy]Benzoic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and reliability for your critical syntheses. Each lot is analyzed using advanced techniques including HPLC, GC, and NMR to verify identity, purity, and impurity profiles. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment, and we support compliance with REACH and other global regulatory frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	142 - 146 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.