Description

Stearoyl-(Carbonyl-14C)-Coenzyme A is a radiolabeled biochemical reagent where the carbonyl carbon of the stearoyl moiety is replaced with the carbon-14 isotope. This compound is essential for tracing and quantifying metabolic pathways involving fatty acid activation and β-oxidation in biochemical and pharmacological research. It is a critical tool for scientists in lipid metabolism studies, enzyme kinetics analysis, and drug discovery programs focused on metabolic diseases.

Application

• Tracer Studies in Lipid Metabolism: Used to elucidate the pathways of stearic acid activation, transport, and degradation within cells and organelles.
• Enzyme Assay Substrate: Serves as a specific radiolabeled substrate for assays involving acyl-CoA synthetases, thioesterases, and other enzymes in fatty acid metabolism.
• Drug Discovery & Pharmacology: Employed in high-throughput screening and mechanistic studies to identify and characterize inhibitors or modulators of enzymes that process long-chain acyl-CoAs.
• Biochemical Research: Facilitates the study of protein acylation, lipid signaling, and the role of stearoyl-CoA in cellular processes.
• Metabolic Flux Analysis: Enables precise tracking of carbon flow through complex metabolic networks in vitro and in vivo.

Basic Information

Product Name	Stearoyl-(Carbonyl-14C)-Coenzyme A
CAS No.	72078-27-4
Molecular Formula	C39H68N7O17P3S * (14C)
Molecular Weight	~1000.9 g/mol (unlabeled)
Synonyms	Stearoyl-Coenzyme A (carbonyl-14C); [1-14C]Stearoyl-CoA; Octadecanoyl-Coenzyme A (carbonyl-14C); 14C-Stearoyl-CoA; Coenzyme A, S-octadecanoyl-, (carbonyl-14C)-; Radiolabeled Stearoyl CoA; Acyl-CoA (18:0, carbonyl-14C); Fatty Acyl-CoA Tracer
EINECS	Contact for details

Quality Control

Every batch of Stearoyl-(Carbonyl-14C)-Coenzyme A is manufactured and analyzed under strict quality protocols to ensure high radiochemical purity and specific activity. Our products undergo rigorous quality testing, including HPLC and TLC analysis, to ensure compliance with research standards. Certificates of Analysis (COA) detailing specific activity, purity, and solvent composition are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at or below -20°C under an inert atmosphere. Avoid repeated freeze-thaw cycles. Keep the material in the original container in a designated radioactive storage area.

Specification

Item	Specification
Appearance	Solution (color may vary)
Identification (HPLC/TLC)	Conforms to standard
Radiochemical Purity	≥ 95%
Specific Activity	50-60 mCi/mmol (Contact for exact value)
Concentration	Customizable (e.g., 0.1 mCi/mL in ethanol)
Solvent	Ethanol or customized aqueous buffer

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.