Description

5B,19-Cycloandrostane-3,17-Dione-D2 is a deuterated steroid derivative, specifically a labeled analog of a key androstane dione intermediate. This compound is of significant value for research and development in pharmaceutical and analytical chemistry, where isotopic labeling is essential. It is primarily needed by scientists and manufacturers in the pharmaceutical, biotechnology, and contract research sectors for use as a stable isotope-labeled internal standard, metabolite reference material, or a synthetic precursor in deuterium tracer studies.

Application

• Internal Standard for Mass Spectrometry: Used in LC-MS/MS and GC-MS bioanalytical methods for the precise quantification of steroid hormones and their metabolites in complex biological matrices.
• Metabolite Reference Standard: Serves as a critical certified reference material (CRM) for identifying and characterizing drug metabolites in pharmacokinetic and metabolism studies.
• Deuterium-Labeled Synthetic Intermediate: Employed in the synthesis of more complex deuterated pharmaceutical compounds for drug discovery and development programs.
• Biochemical Research: Utilized in mechanistic studies of steroidogenesis, enzyme function, and metabolic pathways where tracking with stable isotopes is required.
• Quality Control & Method Development: Acts as a high-purity standard for calibrating analytical instruments and validating new testing protocols in regulatory environments.

Basic Information

Product Name	5B,19-Cycloandrostane-3,17-Dione-D2
CAS No.	71995-57-8
Molecular Formula	C19H26D2O2
Molecular Weight	290.44 g/mol
Synonyms	5β,19-Cycloandrostane-3,17-dione-2,2,4,4-d4 (common labeling pattern); 3,17-Dioxo-5β,19-cycloandrostane-d2; Deuterated 5β,19-Cycloandrostanedione; [2,2,4,4-D4]-5β,19-Cycloandrostane-3,17-dione; Androstane-3,17-dione-d2 (5β,19-cyclo); 19,19-cyclopropanoandrostane-3,17-dione deuterated; 5β,19-Cyclo-5α-androstane-3,17-dione-d2
EINECS	Contact for details

Quality Control

Our 5B,19-Cycloandrostane-3,17-Dione-D2 is produced and handled under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for chemical purity, NMR and MS for structural confirmation and isotopic enrichment, and tests for residual solvents and moisture. Certificates of Analysis (COA) detailing all specifications and test results are available upon request to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to minimize exposure to atmospheric humidity. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure and labeling pattern
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment (MS)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.