Description

(Trifluoromethyl)Benzoic Acid is a high-purity aromatic carboxylic acid derivative characterized by the presence of a trifluoromethyl group, which imparts unique electronic and steric properties. This compound serves as a versatile and critical building block in advanced organic synthesis, enabling the introduction of fluorine-containing motifs that are essential for modulating the biological activity and physicochemical properties of target molecules. It is primarily sought after by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and materials science sectors for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of drugs targeting central nervous system (CNS) disorders, anti-inflammatory agents, and anticancer therapies.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances lipophilicity and metabolic stability.
• Liquid Crystal & OLED Materials: Acts as a precursor for fluorine-containing compounds used in electronic displays and organic light-emitting diodes (OLEDs) to improve performance and stability.
• Polymer & Resin Modifier: Incorporated into specialty polymers to alter thermal stability, chemical resistance, and surface properties.
• Coordination Chemistry & Ligand Synthesis: Utilized to prepare sophisticated ligands for catalysis and metal-organic frameworks (MOFs).
• Academic & Industrial R&D: Serves as a fundamental reagent in medicinal chemistry and material science research for structure-activity relationship (SAR) studies.

Basic Information

Product Name	(Trifluoromethyl)Benzoic Acid
CAS No.	71990-01-7
Molecular Formula	C8H5F3O2
Molecular Weight	190.12 g/mol
Synonyms	3-(Trifluoromethyl)benzoic acid; m-Trifluoromethylbenzoic acid; 3-Trifluoromethylbenzoic acid; Benzoic acid, 3-(trifluoromethyl)-; α,α,α-Trifluoro-m-toluic acid; m-Carboxybenzotrifluoride; 3-Carboxybenzotrifluoride; 3-TFMBA
EINECS	Contact for details

Quality Control

Our (Trifluoromethyl)Benzoic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications in cGMP environments and demanding R&D projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases, strong oxidizing agents, and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	105°C - 110°C
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals (as Pb)	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.