Description

Reboxetine Mesylate is the mesylate salt form of the selective norepinephrine reuptake inhibitor (NRI) reboxetine. This compound is a key pharmaceutical intermediate and active pharmaceutical ingredient (API) of significant commercial and therapeutic importance. It is primarily utilized in the research, development, and manufacturing of antidepressant medications. Industries requiring high-purity, reliable chemical supply for pharmaceutical synthesis are the primary target for this product.

Application

• Pharmaceutical Active Ingredient (API): Primary use in the formulation of antidepressant drugs targeting norepinephrine reuptake inhibition.
• Reference Standard: Serves as a certified reference material (CRM) for analytical method development and quality control in pharmaceutical laboratories.
• Biochemical Research: Used in neuroscience and pharmacology studies to investigate the role of norepinephrine in depression and other central nervous system disorders.
• Process Development: Employed in the scale-up and optimization of synthetic routes for commercial pharmaceutical manufacturing.
• Generic Drug Manufacturing: A critical component for companies producing generic versions of norepinephrine reuptake inhibitor medications.

Basic Information

Item	Detail
Product Name	Reboxetine Mesylate
CAS No.	71620-89-8
Molecular Formula	C19H23NO3 • CH4O3S
Molecular Weight	409.50 g/mol
Synonyms	Reboxetine methanesulfonate; FCE 20124; (R*,R*)-2-[(2-Ethoxyphenoxy)phenylmethyl]morpholine methanesulfonate; (R,R)-Reboxetine Mesylate; Reboxetine mesilate; Norepinephrine Reuptake Inhibitor Reboxetine Mesylate; Edronax (brand name derivative)
EINECS	Contact for details

Quality Control

Our Reboxetine Mesylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling via HPLC, to ensure it meets stringent pharmaceutical-grade specifications. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance with relevant standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.5%
Related Substances (HPLC)	Total impurities ≤ 1.0% Any single impurity ≤ 0.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.