Description

(2S,3R)-3-Hydroxy-2-Methyl-Butanoic Acid CAS NO 71526-30-2 is a high-purity chiral hydroxy acid, a valuable building block in asymmetric synthesis. Its defined stereochemistry is critical for producing enantiomerically pure compounds, ensuring consistent performance and efficacy in advanced applications. This compound is essential for research and production in the pharmaceutical, agrochemical, and specialty chemical industries, where precise molecular architecture dictates function.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in antiviral, antibiotic, and cardiovascular drug development.
• Agrochemical Synthesis: Used in the production of enantiomerically pure herbicides, fungicides, and plant growth regulators for enhanced efficacy and environmental safety.
• Fine Chemical Building Block: Serves as a precursor for complex molecules in flavors, fragrances, and advanced material science.
• Biocatalyst & Enzyme Substrate: Employed in enzymatic studies and as a substrate for developing stereoselective biocatalytic processes.
• Ligand & Catalyst Development: Utilized in the preparation of chiral ligands and organocatalysts for asymmetric catalysis.
• Academic & Industrial R&D: A fundamental reagent for methodological research in organic chemistry and process development.

Basic Information

Item	Details
Product Name	(2S,3R)-3-Hydroxy-2-Methyl-Butanoic Acid
CAS No.	71526-30-2
Molecular Formula	C5H10O3
Molecular Weight	118.13 g/mol
Synonyms	(2S,3R)-3-Hydroxy-2-methylbutyric acid; (2S,3R)-2-Methyl-3-hydroxybutanoic acid; L-threo-3-Hydroxy-2-methylbutyric acid; (2S,3R)-Hydroxymethylbutanoic acid; 3-Hydroxy-2-methylbutyric acid (specifying stereochemistry); 71526-30-2; (S,R)-3-Hydroxy-2-methylbutanoate
EINECS	Contact for details

Quality Control

Our (2S,3R)-3-Hydroxy-2-Methyl-Butanoic Acid is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical and fine chemical applications. Certificates of Analysis (COA) detailing identity, assay, enantiomeric excess, and impurity profiles are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation and maintain purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.