Description

(+/-)12-Hete CAS NO 71030-37-0 is a high-purity hydroxy fatty acid derivative, specifically a hydroxy-eicosatetraenoic acid, valued for its role as a key biochemical intermediate and research standard. This compound is essential for studying lipid signaling pathways, inflammation, and cellular regulation mechanisms. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and advanced chemical synthesis sectors for developing novel therapeutic agents and conducting critical metabolic studies.

Application

• Biochemical Research: Serves as a critical standard and precursor in the study of eicosanoid biology, lipoxygenase pathways, and inflammatory mediators.
• Pharmaceutical Development: Used as an intermediate in the synthesis of potential drug candidates targeting metabolic disorders and inflammatory diseases.
• Cell Signaling Studies: Employed in vitro and in vivo to investigate the effects of hydroxy fatty acids on cellular function and receptor interactions.
• Reference Material: Acts as a high-purity analytical standard for method development and validation in chromatographic (HPLC, GC) and mass spectrometric analyses.
• Metabolic Pathway Analysis: Utilized in metabolic profiling and lipidomics research to understand the role of specific HETE isomers in physiological and pathological processes.
• Enzymology: Functions as a substrate or product in enzymatic assays for lipoxygenases and related enzymes.

Basic Information

Product Name	(+/-)12-Hete
CAS No.	71030-37-0
Molecular Formula	C20H32O3
Molecular Weight	320.47 g/mol
Synonyms	12-HETE; (±)-12-HETE; 12(S)-HETE Racemate; 12-Hydroxy-5Z,8Z,10E,14Z-eicosatetraenoic Acid; 12-Hydroxyeicosatetraenoic Acid; 12(S)-Hydroxy-5,8,10,14-eicosatetraenoic Acid; 12-Lipoxygenase Metabolite; 12-Hydroxyicosa-5,8,10,14-tetraenoic Acid
EINECS	Contact for details

Quality Control

Our (+/-)12-Hete is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing specific results for purity, assay, and related substances is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the sealed container to reach room temperature before opening to minimize moisture condensation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow oil or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
Assay	≥ 98%
Solubility	Soluble in ethanol, DMSO, and common organic solvents

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.