Description

15(S)-Hydroxy-(5Z,8Z,11Z,13E)-Eicosatetraenoic Acid is a specialized hydroxy fatty acid and a key metabolite of arachidonic acid, playing a significant role in cellular signaling pathways. This compound is valued for its high purity and structural specificity, making it an essential reference standard and research tool. It is primarily used by researchers and developers in the pharmaceutical, biotechnology, and life science sectors for studying inflammation, cell biology, and metabolic processes.

Application

• Biochemical Research: Used as a critical reference standard and analytical standard in lipidomics and eicosanoid research.
• Pharmaceutical Development: Serves as a key intermediate or biological probe for investigating inflammatory pathways and developing novel therapeutic agents.
• Cell Signaling Studies: Employed in vitro and in vivo to study the role of hydroxyeicosatetraenoic acids (HETEs) in cellular communication and disease mechanisms.
• Enzymology: Acts as a substrate or product for studies involving lipoxygenase and cytochrome P450 enzyme activities.
• Diagnostic Reagent Manufacturing: Utilized in the production of high-sensitivity assay kits for detecting and quantifying eicosanoid levels in biological samples.

Basic Information

Product Name	15(S)-Hydroxy-(5Z,8Z,11Z,13E)-Eicosatetraenoic Acid
CAS No.	70946-44-0
Molecular Formula	C₂₀H₃₂O₃
Molecular Weight	320.47 g/mol
Synonyms	15(S)-HETE; 15S-HETE; (15S)-Hydroxy-5Z,8Z,11Z,13E-eicosatetraenoic Acid; 15S-Hydroxyeicosatetraenoic Acid; 15(S)-Hydroxy-5,8,11,13-eicosatetraenoic Acid; 15S-Hydroxyarachidonic Acid; 15(S)-HETE; 15-HETE (S-isomer)
EINECS	Contact for details

Quality Control

Every batch of 15(S)-HETE is produced and analyzed under strict quality management protocols to ensure identity, purity, and consistency. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with research-grade standards. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the product to reach room temperature in a desiccator before opening to minimize moisture uptake. Keep away from strong oxidizers.

Specification

Item	Specification
Appearance	Colorless to pale yellow oil or solid
Identification (HPLC/MS)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Purity (HPLC, Area %)	≥ 98.0%
Optical Purity (Chiral HPLC)	≥ 98.0% ee (15S-isomer)
Solubility	Soluble in ethanol, DMSO, DMF; slightly soluble in aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.