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D-[11-13C]Talose CAS NO 70849-29-5
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CAS No.:70849-29-5
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
D-[11-13C]Talose is a stable isotope-labeled analog of the rare sugar D-talose, specifically enriched with carbon-13 at the C-11 to C-13 positions. This compound is a critical tool for advanced metabolic and biochemical research, enabling precise tracing and quantification of carbohydrate pathways. It is primarily utilized by research institutions and pharmaceutical companies engaged in isotope dilution mass spectrometry (IDMS), metabolic flux analysis, and the development of novel diagnostic agents.
Application
- Metabolic Pathway Tracing: As a 13C-labeled tracer for studying the metabolism of rare sugars and related glycan biosynthesis in biological systems.
- Isotope Dilution Mass Spectrometry (IDMS): Serves as an internal standard for the accurate quantification of D-talose and its derivatives in complex matrices.
- Pharmaceutical Research: Used in the development and validation of assays for drug metabolism and pharmacokinetic (DMPK) studies involving carbohydrate-based therapeutics.
- Glycobiology Studies: Aids in the investigation of enzyme mechanisms, carbohydrate-protein interactions, and the structure-function relationships of glycoconjugates.
- Nutritional Science Research: Employed to trace the fate and utilization of specific sugar isomers in nutritional studies and gut microbiome research.
- Diagnostic Agent Development: Potential use as a labeled precursor in the synthesis of contrast agents or probes for medical imaging techniques like PET (Positron Emission Tomography).
Basic Information
| Item | Detail |
|---|---|
| Product Name | D-[11-13C]Talose |
| CAS No. | 70849-29-5 |
| Molecular Formula | C6H12O6 (with 13C enrichment at specified positions) |
| Molecular Weight | ~181.1 g/mol (exact value depends on isotopic enrichment level) |
| Synonyms | D-Talose-13C3; (3R,4S,5R,6R)-6-(Hydroxymethyl)oxane-2,3,4,5-tetrol-13C3; 6-Deoxy-L-talose-13C3 (related isomer); Isotopically Labeled D-Talose; Carbon-13 Labeled Talose; 13C3-D-Talose; Stable Isotope-Labeled Hexose |
| EINECS | Contact for details |
Quality Control
Every batch of D-[11-13C]Talose is produced and analyzed under strict quality management protocols. We guarantee high chemical and isotopic purity, with comprehensive characterization via NMR, HPLC, and Mass Spectrometry. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting the isotopic enrichment, chemical purity, and results of all identity and purity tests. Our quality system ensures traceability and compliance with the stringent requirements of research and development applications.
Storage
Preserve in a tightly closed container, protected from light. Store at 2-8°C in a cool, dry place. This product is hygroscopic (moisture-sensitive). For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white solid |
| Identification (NMR) | Conforms to structure |
| Isotopic Enrichment | ≥ 99 atom % 13C at specified positions |
| Chemical Purity (HPLC) | ≥ 98.0% |
| Specific Optical Rotation | Contact for details |
| Water Content (KF) | ≤ 1.0% |
| Residual Solvents (GC) | Complies with ICH guidelines |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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