Description

(-)-Diacetyl-D-Tartaric Anhydride is a high-purity chiral building block and resolving agent of significant importance in asymmetric synthesis. Its primary value lies in its ability to facilitate the separation of enantiomers and serve as a key intermediate for producing optically active compounds. This material is essential for research and production in the pharmaceutical, agrochemical, and fine chemical industries, where precise stereochemistry is critical for product efficacy and regulatory approval.

Application

• Chiral Resolution Agent: Widely used for the separation of racemic mixtures of amines, amino acids, and other basic pharmaceuticals.
• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs) requiring specific D-tartaric acid derivatives.
• Asymmetric Synthesis Catalyst/Reagent: Employed in reactions to induce chirality and create enantiomerically enriched products.
• Fine Chemical Synthesis: Used in the production of specialty chemicals, flavors, and fragrances where optical purity is paramount.
• Analytical Chemistry: Utilized as a derivatizing agent for chromatographic analysis to separate and identify enantiomers.
• Agrochemical Production: Intermediate in the manufacture of chiral herbicides, fungicides, and plant growth regulators.

Basic Information

Item	Detail
Product Name	(-)-Diacetyl-D-Tartaric Anhydride
CAS No.	70728-23-3
Molecular Formula	C8H8O7
Molecular Weight	216.15 g/mol
Synonyms	(-)-Diacetyl-D-tartaric anhydride; (2R,3R)-2,3-Diacetyloxybutanedioic anhydride; D-(-)-Diacetyl tartaric anhydride; DATAN; D-DTAA; Anhydride of D-(-)-Diacetyl tartaric acid; (R,R)-(-)-Diacetyl tartaric anhydride; Butanedioic acid, 2,3-bis(acetyloxy)-, (2R,3R)-, anhydride
EINECS	Contact for details

Quality Control

Our (-)-Diacetyl-D-Tartaric Anhydride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assay and impurity profiling, to ensure it meets the stringent requirements for chiral intermediates. Certificates of Analysis (COA) documenting identity, purity, and specific rotation are provided with every shipment to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity ([α]D)	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.