Description

Oleic Acid-1-13C, Methyl Ester CAS NO 70491-68-8 is a stable isotope-labeled derivative of oleic acid methyl ester, where the carbon-13 isotope is specifically incorporated at the carboxyl carbon position. This precise labeling makes it an indispensable internal standard and tracer in advanced mass spectrometry and nuclear magnetic resonance (NMR) studies. It is primarily required by researchers and analytical laboratories in the pharmaceutical, nutritional science, and metabolic research sectors for quantitative analysis, metabolic pathway elucidation, and method validation.

Application

• Quantitative Mass Spectrometry (MS) & GC-MS: Serves as a critical internal standard for the accurate quantification of oleic acid and its derivatives in complex biological matrices like plasma, tissues, and food products.
• Metabolic Flux Analysis (MFA): Used as a stable isotope tracer to investigate lipid metabolism, fatty acid oxidation, and biosynthetic pathways in cell cultures, animal models, and clinical research.
• NMR Spectroscopy: Provides a distinct 13C signal for structural analysis and dynamic studies of lipid assemblies, membrane biophysics, and protein-lipid interactions.
• Pharmaceutical R&D: Essential in drug metabolism and pharmacokinetics (DMPK) studies to track the fate of lipid-based drug formulations and active pharmaceutical ingredients.
• Nutritional & Biomedical Research: Enables precise studies on fatty acid absorption, bioavailability, and their role in health and disease states such as obesity, diabetes, and cardiovascular conditions.
• Method Development & Validation: Used to develop, calibrate, and validate analytical methods in compliance with guidelines from regulatory bodies like the FDA and EMA.
• Quality Control in Lipidomics: Acts as a reference standard to ensure accuracy and reproducibility in high-throughput lipid profiling and omics studies.

Basic Information

Item	Details
Product Name	Oleic Acid-1-13C, Methyl Ester
CAS No.	70491-68-8
Molecular Formula	C₁₉H₃₆¹³COOCH₃ / C₁₉H₃₆O₂ (¹³C-labeled)
Molecular Weight	~297.5 g/mol (¹³C-adjusted)
Synonyms	(Z)-Octadec-9-enoic-1-13C acid methyl ester; Methyl (9Z)-octadec-9-enoate-1-13C; Methyl oleate-1-13C; 13C Labeled methyl oleate; 9-Octadecenoic acid (9Z)-, methyl ester, 1-13C; Oleic acid methyl ester-1-13C; 13C1-Methyl oleate; Isotope-labeled lipid standard
EINECS	Contact for details

Quality Control

Every batch of Oleic Acid-1-13C, Methyl Ester is produced and analyzed under strict quality management protocols to ensure exceptional isotopic and chemical purity, which is critical for sensitive analytical applications. Our products undergo rigorous quality testing, including isotopic enrichment verification by NMR and MS, to ensure compliance with the high standards required for research and diagnostics. Certificates of Analysis (COA) detailing batch-specific purity, isotopic enrichment, and analytical results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere for long-term stability. This product is easily oxidized and should be handled under appropriate conditions to maintain isotopic integrity and chemical purity. Allow the sealed vial to equilibrate to room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR/NMR)	Conforms to structure
Isotopic Enrichment (13C)	≥ 99 atom % 13C
Chemical Purity (GC)	≥ 98%
Isomeric Purity (Z-isomer)	≥ 99%
Water Content (KF)	≤ 0.1%
Solvent Residue (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.