Description

Ambenonium is a synthetic, quaternary ammonium compound known for its potent and long-acting anticholinesterase activity. This pharmacological property makes it a critical agent for modulating cholinergic signaling in research and development contexts. It is primarily utilized by pharmaceutical researchers, contract development and manufacturing organizations (CDMOs), and fine chemical suppliers serving the life sciences sector. The compound is supplied under stringent quality controls to ensure batch-to-batch consistency for demanding applications.

Application

• Pharmacological Research: Used as a reference standard and active agent in studies investigating neuromuscular transmission, myasthenia gravis, and cholinergic pathways.
• Biochemical Assay Development: Serves as a key inhibitor in enzymatic assays targeting acetylcholinesterase and butyrylcholinesterase for drug discovery screening.
• Pharmaceutical Intermediate: Employed in the synthesis and development of novel therapeutic agents targeting the cholinergic system.
• Academic Research: Utilized in university and institutional labs for neuropharmacology and toxicology studies.
• Reference Standard: Sourced by analytical laboratories for method development, validation, and quality control testing.

Basic Information

Product Name	Ambenonium
CAS No.	7648-98-8
Molecular Formula	C28H42Cl2N4O2
Molecular Weight	537.57 g/mol
Synonyms	Ambenonium Chloride; WIN 8077; Mysuran; Mytelase; Oxazyl; N,N'-Bis(2-diethylaminoethyl)oxamide bis(2-chlorobenzyl) chloride; 1,1'-[Oxalylbis(iminoethylene)]bis[2-chloro-N,N-diethylbenzenaminium] Dichloride
EINECS	231-615-7

Quality Control

Our Ambenonium is manufactured and tested under a strict quality management system. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We ensure compliance with relevant standards for research-grade materials, and specifications can be aligned with client-specific pharmacopeial requirements (e.g., USP, EP) upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.