Description

tert-Butylmethylphenylphosphine CAS NO 7621-16-1 is a versatile and highly valuable tertiary phosphine ligand used in organometallic chemistry and catalysis. Its primary importance lies in its ability to facilitate and accelerate key cross-coupling reactions, enabling the efficient synthesis of complex organic molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require high-performance catalysts for fine chemical and active pharmaceutical ingredient (API) production.

Application

• As a ligand in transition metal catalysis, particularly for palladium-catalyzed cross-coupling reactions like Suzuki, Heck, and Negishi couplings.
• Critical component in homogeneous catalyst systems for the synthesis of pharmaceuticals and agrochemical intermediates.
• Used in asymmetric synthesis when incorporated into chiral catalyst frameworks for producing enantiomerically pure compounds.
• Facilitates polymerization reactions, such as olefin polymerization, when used with appropriate metal centers.
• Employed in academic and industrial R&D for developing new catalytic methodologies and exploring novel reaction pathways.
• Acts as a stabilizing agent for reactive organometallic complexes and nanoparticles.

Basic Information

Product Name	tert-Butylmethylphenylphosphine
CAS No.	7621-16-1
Molecular Formula	C11H17P
Molecular Weight	180.22 g/mol
Synonyms	Methyl(tert-butyl)phenylphosphine; (tert-Butyl)(methyl)phenylphosphine; tert-Butylmethylphenylphosphane; P-(tert-Butyl)-P-methylphenylphosphine; Phenyl(tert-butyl)methylphosphine; t-BuMePhP; Phosphine, methyl(1,1-dimethylethyl)phenyl-; Methyl-tert-butyl-phenyl-phosphine
EINECS	Contact for details

Quality Control

Our tert-Butylmethylphenylphosphine is produced under stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including NMR (¹H, ³¹P, ¹³C), GC, and HPLC analysis, to verify identity and assay. Certificates of Analysis (COA) detailing all test results are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Due to its nature as an easily oxidized compound, it must be stored under an inert atmosphere (argon or nitrogen) in a cool, dry place. Recommended long-term storage temperature is 2-8°C. Handle and dispense in a controlled, moisture-free environment to maintain stability and purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (NMR)	Conforms to structure
Purity (GC)	≥ 97.0%
Assay (NMR)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.