Description

Atropine Nitrate CAS NO 7459-97-4 is the nitrate salt form of the well-known anticholinergic alkaloid atropine. This compound is a critical pharmaceutical active ingredient and research chemical, valued for its high purity and consistent performance. It is primarily required by manufacturers in the pharmaceutical, biotechnology, and life science research sectors for the formulation of ophthalmic solutions, specific antidotes, and as a key reference standard in analytical laboratories.

Application

• Pharmaceutical Manufacturing: Key intermediate and active pharmaceutical ingredient (API) in the production of ophthalmic solutions for pupil dilation and cycloplegia.
• Antidote Formulation: Essential component in injectable antidotes for organophosphate and carbamate pesticide or nerve agent poisoning.
• Biomedical Research: Used as a potent, non-selective muscarinic acetylcholine receptor antagonist in pharmacological and physiological studies.
• Reference Standard: Serves as a high-purity certified reference material (CRM) for quality control and analytical method development in laboratories.
• Veterinary Medicine: Employed in veterinary pharmaceuticals for similar antispasmodic and antisecretory applications as in human medicine.

Basic Information

Product Name	Atropine Nitrate
CAS No.	7459-97-4
Molecular Formula	C17H23N3O6
Molecular Weight	365.38 g/mol
Synonyms	Atropine Mononitrate; DL-Hyoscyamine Nitrate; Tropine Tropate Nitrate; 8-Methyl-8-azabicyclo[3.2.1]oct-3-yl 3-hydroxy-2-phenylpropanoate nitrate; Atropinol Nitrate; Atropinium Nitrate; (±)-Hyoscyamine Nitrate
EINECS	231-246-5

Quality Control

Our Atropine Nitrate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for assay and related substances, to ensure it meets stringent pharmacopeial standards such as USP, EP, and BP. A detailed Certificate of Analysis (COA) documenting purity, identity, and all critical parameters is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White or almost white, crystalline powder
Identification (IR)	Conforms to standard
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Specific Rotation	-0.10° to +0.10° (c = 5 in H2O)
pH (5% solution)	4.5 - 6.0
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any individual impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.