Description

2',3'-Dideoxy-2',3'-Didehydroadenosine is a synthetic nucleoside analog of significant interest in medicinal chemistry and biochemical research. This compound serves as a key intermediate and building block in the synthesis of modified nucleotides and potential antiviral agents. It is primarily utilized by pharmaceutical R&D laboratories, biotechnology companies, and academic institutions engaged in drug discovery and nucleic acid chemistry.

Application

• Pharmaceutical Intermediate: Critical building block for the synthesis of nucleoside-based antiviral and anticancer prodrugs.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies involving polymerases and reverse transcriptases.
• Antiviral Agent Development: Serves as a core structure for developing novel dideoxynucleoside analogs targeting viral replication.
• Nucleic Acid Chemistry: Employed in the study of DNA/RNA structure, function, and the mechanisms of chain termination.
• Proteomics & Genomics: Used in the development of probes and tools for studying cellular processes and genetic regulation.
• Reference Standard: Sourced for use as a high-purity analytical standard in quality control and method development.

Basic Information

Product Name	2',3'-Dideoxy-2',3'-Didehydroadenosine
CAS No.	7057-48-9
Molecular Formula	C10H11N5O2
Molecular Weight	233.23 g/mol
Synonyms	2',3'-Didehydro-2',3'-dideoxyadenosine; D4A; ddA; 9-[(2R,5S)-5-(Hydroxymethyl)-2,5-dihydrofuran-2-yl]-9H-purin-6-amine; 2',3'-Unsaturated-2',3'-dideoxyadenosine; NSC 669229; 2',3'-Dideoxy-2',3'-dehydroadenosine
EINECS	Contact for details

Quality Control

Our 2',3'-Dideoxy-2',3'-Didehydroadenosine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with research and development grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture uptake. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.