Description

1,3-Dimethylthymine Cyclobutane Dimer is a specialized photodimerization product derived from thymine, a key pyrimidine base in nucleic acids. This compound is of significant interest in photochemistry and molecular biology research, particularly for studying DNA damage and repair mechanisms caused by ultraviolet (UV) light exposure. It serves as a critical reference standard and synthetic intermediate for researchers and manufacturers in the fields of pharmaceutical development, photobiology, and advanced material science.

Application

• Photochemistry Research: As a model compound for studying UV-induced cyclobutane pyrimidine dimer (CPD) formation and photoreactivation.
• Biochemical Standards: Used as a high-purity reference standard in analytical laboratories for quantifying DNA photolesions.
• Pharmaceutical Intermediates: Serves as a building block in the synthesis of novel nucleoside analogs and potential therapeutic agents.
• Molecular Biology Studies: Essential for investigating DNA repair pathways, enzyme kinetics (e.g., photolyases), and mutagenesis.
• Material Science: Potential application in the development of light-responsive polymers and biomimetic materials.

Basic Information

Product Name	1,3-Dimethylthymine Cyclobutane Dimer
CAS No.	7025-74-3
Molecular Formula	C12H16N4O4
Molecular Weight	280.28 g/mol
Synonyms	1,3-Dimethylthymine Dimer; cis,syn-1,3-Dimethylthymine Cyclobutane Dimer; Thymine Dimethyl Dimer; 1,3-Dimethyl-5,6-dihydro-5,6-dihydroxythymine Dimer (related); Cyclobutadithymine, 1,3-Dimethyl-; Photodimer of 1,3-Dimethylthymine; 5,6-Dihydro-5,6-dihydroxy-1,3-dimethyluracil Dimer (related structure)
EINECS	Contact for details

Quality Control

Our 1,3-Dimethylthymine Cyclobutane Dimer is produced under stringent conditions to ensure high chemical purity and batch-to-batch consistency, suitable for sensitive research applications. Quality is verified through advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.