Description

3-(Trifluoromethyl)Cinnamic Acid is a high-value fluorinated aromatic building block characterized by its cinnamic acid core and a strategically positioned trifluoromethyl group. This compound matters for its role in modulating the physicochemical properties of target molecules, enhancing lipophilicity, metabolic stability, and bioavailability. It is primarily needed by researchers and manufacturers in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, as well as in materials science for creating advanced functional polymers.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in oncology, CNS, and anti-inflammatory therapies.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides where the CF₃ group improves activity and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated monomers used in electronic display technologies and organic light-emitting diodes.
• Polymer Modification: Incorporated into polymer chains to enhance thermal stability, chemical resistance, and optical properties of specialty plastics and coatings.
• Chemical Research & Development: Employed in academic and industrial R&D for studying structure-activity relationships and as a versatile scaffold in medicinal chemistry.
• Fluorinated Dye & Pigment Precursor: Used in the synthesis of specialized dyes and pigments with improved lightfastness and solubility characteristics.

Basic Information

Product Name	3-(Trifluoromethyl)Cinnamic Acid
CAS No.	779-89-5
Molecular Formula	C₁₀H₇F₃O₂
Molecular Weight	216.16 g/mol
Synonyms	(E)-3-[3-(Trifluoromethyl)phenyl]prop-2-enoic acid; 3-(Trifluoromethyl)benzeneacrylic acid; trans-3-(3-Trifluoromethylphenyl)acrylic acid; α-(3-Trifluoromethylphenyl)acrylic acid; 3-(α,α,α-Trifluoro-m-tolyl)acrylic acid; m-Trifluoromethylcinnamic acid; 3-CF₃-Cinnamic Acid
EINECS	212-300-3

Quality Control

Our 3-(Trifluoromethyl)Cinnamic Acid is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by FT-IR and NMR, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) with detailed batch-specific results are provided to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	158 - 162 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.