Description

Trimipramine is a tricyclic antidepressant (TCA) compound of significant pharmaceutical importance. It functions primarily as a serotonin-norepinephrine reuptake inhibitor, making it a key active pharmaceutical ingredient (API) in the formulation of antidepressant medications. This compound is essential for pharmaceutical manufacturers and research institutions developing treatments for major depressive disorders and related conditions. Consistent quality and reliable supply are critical for ensuring the efficacy and safety of the final drug product.

Application

• Active Pharmaceutical Ingredient (API): Primary use in the manufacture of antidepressant medications.
• Pharmaceutical Research: Used as a reference standard in analytical laboratories for method development and quality control.
• Neuropharmacology Studies: Employed in preclinical research to study the mechanisms of tricyclic antidepressants and serotonin/norepinephrine pathways.
• Formulation Development: Serves as the core component in the development of various dosage forms, such as tablets and capsules.
• Chemical Synthesis: Acts as a key intermediate or starting material for the synthesis of more complex pharmaceutical molecules or derivatives.

Basic Information

Product Name	Trimipramine
CAS No.	739-71-9
Molecular Formula	C20H26N2
Molecular Weight	294.44 g/mol
Synonyms	5-[3-(Dimethylamino)-2-methylpropyl]-10,11-dihydro-5H-dibenz[b,f]azepine; Surmontil; Rhotrimine; Stangyl; Trimipramine Maleate; Trimipramine Mesylate; TMP
EINECS	Contact for details

Quality Control

Our Trimipramine is produced and tested under strict quality management systems to meet the rigorous standards of the pharmaceutical industry. Each batch undergoes comprehensive analysis, including identity confirmation, purity assay, and impurity profiling using advanced techniques like HPLC and GC. Certificates of Analysis (COA) are provided with every shipment, detailing all test results against relevant pharmacopeial specifications (e.g., USP, EP). We are committed to ensuring batch-to-batch consistency and regulatory compliance for our global partners.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to standard
Identification (HPLC)	Conforms to standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity: ≤ 0.5% Total impurities: ≤ 1.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.