Description

3-(3-Fluorophenyl)Propiolic Acid is a specialized fluorinated aromatic alkyne derivative, serving as a versatile and high-value building block in advanced organic synthesis. Its core value lies in the strategic combination of a reactive propiolic acid moiety and a fluorine-substituted phenyl ring, enabling precise molecular modifications. This compound is essential for research chemists and process development scientists in the pharmaceutical and agrochemical industries, where it is used to create novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of fluorinated drug candidates, particularly for kinase inhibitors and central nervous system (CNS) active compounds.
• Agrochemical Synthesis: Used to incorporate fluorine atoms into novel herbicides, fungicides, and pesticides to enhance their biological activity and environmental stability.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers and advanced organic frameworks with tailored electronic properties.
• Chemical Biology Probes: Employed in click chemistry and bioconjugation strategies to create fluorescent tags and molecular probes for diagnostic applications.
• Academic & R&D: A valuable reagent for methodological studies in organic chemistry, including Sonogashira coupling and other palladium-catalyzed reactions.

Basic Information

Product Name	3-(3-Fluorophenyl)Propiolic Acid
CAS No.	705-83-9
Molecular Formula	C9H5FO2
Molecular Weight	164.13 g/mol
Synonyms	3-(3-Fluorophenyl)prop-2-ynoic acid; 3-Fluorophenylpropiolic Acid; m-Fluorophenylpropiolic Acid; 3-Fluorobenzene propiolic acid; 705-83-9; 3-(3-Fluorophenyl)-2-propynoic acid; Propiolic acid, 3-(3-fluorophenyl)-
EINECS	Contact for details

Quality Control

Our production of 3-(3-Fluorophenyl)Propiolic Acid adheres to stringent in-process controls to ensure batch-to-batch consistency and high purity. Each lot is fully characterized and tested against established specifications, which typically include identity confirmation (IR, NMR), purity assay (HPLC), and control of related substances. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed immediately after use to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.