Description

2,6-Difluoro-4-Hydroxybenzenepropanoic Acid Ethyl Ester is a high-value fluorinated aromatic building block, essential for synthesizing advanced pharmaceutical intermediates and agrochemicals. Its unique difluoro-hydroxy substitution pattern makes it a critical precursor for creating molecules with enhanced biological activity and metabolic stability. This compound is primarily sought by research and development chemists, as well as process development teams, in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring fluorinated compounds for improved bioavailability and target binding.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine atoms contribute to potency and environmental persistence profiles.
• Liquid Crystal Materials: Serves as a precursor in the synthesis of fluorinated liquid crystals for display technologies, leveraging its aromatic and ester functionality.
• Organic Electronics: Potential building block for electron-transport materials or semiconductors in OLEDs and organic photovoltaics due to its conjugated system and fluorine substituents.
• Chemical Research & Development: Employed in academic and industrial R&D labs for method development, catalysis studies, and exploring new reactions of fluorinated aromatics.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses producing specialized fine chemicals for client-specific projects.

Basic Information

Product Name	2,6-Difluoro-4-Hydroxybenzenepropanoic Acid Ethyl Ester
CAS No.	691905-11-0
Molecular Formula	C11H12F2O3
Molecular Weight	230.21 g/mol
Synonyms	Ethyl 3-(4-Hydroxy-2,6-difluorophenyl)propanoate; 2,6-Difluoro-4-hydroxybenzenepropanoic acid ethyl ester; 3-(4-Hydroxy-2,6-difluorophenyl)propionic Acid Ethyl Ester; Ethyl 2,6-Difluoro-4-hydroxyhydrocinnamate; 4-Hydroxy-2,6-difluorohydrocinnamic Acid Ethyl Ester; Benzenepropanoic acid, 2,6-difluoro-4-hydroxy-, ethyl ester; CAS 691905-11-0
EINECS	Contact for details

Quality Control

Every batch of 2,6-Difluoro-4-Hydroxybenzenepropanoic Acid Ethyl Ester is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the precise requirements for advanced synthetic applications. A detailed Certificate of Analysis (COA), including results from HPLC, NMR, and GC-MS, is supplied with each shipment to guarantee identity, purity, and consistency for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider inert atmosphere conditions to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.