Description

Nesbuvir CAS NO 691852-58-1 is a high-purity pharmaceutical intermediate and active ingredient of significant importance in antiviral research and development. This compound is a key building block in the synthesis of novel therapeutic agents targeting specific viral enzymes. It is primarily required by pharmaceutical manufacturers, contract research organizations (CROs), and academic research institutions engaged in the discovery and production of next-generation antiviral medications.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of active pharmaceutical ingredients (APIs) for antiviral drugs.
• Antiviral Drug Research: Used as a reference standard and building block in medicinal chemistry for developing new therapeutic candidates against viral infections.
• Biochemical Research: Employed in in vitro studies to investigate mechanisms of action and inhibition kinetics of viral polymerases or proteases.
• Process Development & Scale-up: Utilized by process chemists to optimize synthetic routes for cost-effective and scalable manufacturing of target molecules.
• Quality Control & Analytical Standards: Functions as a high-purity certified reference material (CRM) for HPLC, LC-MS, and NMR analysis in quality assurance laboratories.

Basic Information

Product Name	Nesbuvir
CAS No.	691852-58-1
Molecular Formula	C22H29FN3O9P
Molecular Weight	529.46 g/mol
Synonyms	PSI-6130; 2'-Deoxy-2'-fluoro-2'-C-methylcytidine 5'-(trihydrogen diphosphate); RO-2433; β-D-2'-Deoxy-2'-fluoro-2'-C-methylcytidine-5'-triphosphate; 2'-F-2'-C-Methylcytidine Triphosphate; 2'-Fluoro-2'-C-methylcytidine-5'-triphosphate
EINECS	Contact for details

Quality Control

Our Nesbuvir is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and assay, NMR and MS for structural confirmation, and tests for residual solvents and related substances to ensure it meets stringent specifications for pharmaceutical R&D use. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. This product is hygroscopic (moisture-sensitive) and should be handled under a dry, inert atmosphere to maintain stability and prevent decomposition. Allow the sealed container to reach room temperature before opening to avoid condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Assay (HPLC)	97.0% - 103.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.