Description

8-Iodo-1-Naphthoic Anhydride is a high-purity, halogenated naphthalene derivative used as a versatile synthetic intermediate. This compound is valued for its reactivity, particularly in coupling reactions and as a precursor for constructing complex organic frameworks. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require a reliable building block for developing new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel active pharmaceutical ingredients (APIs), especially for compounds targeting specific receptors.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides, leveraging its halogenated structure for bioactivity.
• Material Science: Serves as a precursor for organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors.
• Cross-Coupling Reactions: An effective substrate in palladium-catalyzed reactions like Suzuki, Stille, and Sonogashira couplings for carbon-carbon bond formation.
• Ligand and Catalyst Synthesis: Used to create complex ligands for metal catalysts used in asymmetric synthesis.
• Dye and Pigment Intermediate: Employed in the synthesis of specialized dyes and pigments due to the naphthalene core.
• Academic & R&D: A valuable reagent for methodological studies and exploring new synthetic pathways in organic chemistry.

Basic Information

Product Name	8-Iodo-1-Naphthoic Anhydride
CAS No.	680211-26-1
Molecular Formula	C22H10I2O3
Molecular Weight	592.12 g/mol
Synonyms	1,8-Naphthalenedicarboxylic Anhydride, 4,5-diiodo-; 4,5-Diiodonaphthalic Anhydride; 8-Iodonaphthalic Anhydride; 4,5-Diiodo-1,8-naphthalic anhydride; Diiodonaphthalic Anhydride; 1H,3H-Naphtho[1,8-cd]pyran-1,3-dione, 6,7-diiodo-
EINECS	Contact for details

Quality Control

Our 8-Iodo-1-Naphthoic Anhydride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including HPLC, NMR, and elemental analysis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your R&D and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if possible to prevent degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Loss on Drying	< 1.0%
Residue on Ignition	< 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.