Description

5-Chloro-2-Fluoro-4-Methoxyphenylboronic Acid is a high-purity boronic acid derivative, a critical building block in modern synthetic chemistry. Its value lies in enabling precise carbon-carbon bond formation via the Suzuki-Miyaura cross-coupling reaction, a cornerstone for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials industries, where it is used to develop active pharmaceutical ingredients (APIs), novel crop protection agents, and organic electronic materials.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of complex drug candidates and active pharmaceutical ingredients (APIs), particularly in medicinal chemistry research.
• Agrochemical Synthesis: Used in constructing novel herbicides, fungicides, and insecticides with specific activity profiles.
• Material Science: Serves as a monomer or building block for creating organic semiconductors, liquid crystals, and metal-organic frameworks (MOFs).
• Chemical Research & Development: Fundamental reagent in academic and industrial R&D for exploring new Suzuki-Miyaura coupling methodologies and creating bespoke chemical libraries.
• Ligand Synthesis: Precursor for the development of specialised ligands used in catalysis and coordination chemistry.

Basic Information

Product Name	5-Chloro-2-Fluoro-4-Methoxyphenylboronic Acid
CAS No.	677741-96-7
Molecular Formula	C7H7BClFO3
Molecular Weight	203.39 g/mol
Synonyms	(5-Chloro-2-fluoro-4-methoxyphenyl)boronic acid; 2-Fluoro-5-chloro-4-methoxybenzeneboronic acid; 5-Chloro-2-fluoro-4-methoxybenzeneboronic acid; 4-Methoxy-5-chloro-2-fluorophenylboronic acid; Boronic acid, B-(5-chloro-2-fluoro-4-methoxyphenyl)-; CAS 677741-96-7
EINECS	Contact for details

Quality Control

Our 5-Chloro-2-Fluoro-4-Methoxyphenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high chemical purity and consistent performance. Certificates of Analysis (COA) detailing batch-specific results are provided to guarantee traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.