Description

2-(2-Fluoro-Benzoyl)-3-Oxo-Butyric Acid Ethyl Ester is a high-purity fluorinated organic building block of significant interest in advanced chemical synthesis. This compound serves as a critical intermediate for constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and specialty agrochemicals. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for its versatile reactivity profile.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of fluorinated drug candidates, including potential kinase inhibitors and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the research and development of novel herbicides and pesticides, leveraging the fluorine atom for enhanced bioactivity and stability.
• Fine Chemical Production: Serves as a versatile building block for creating complex esters, diketones, and heterocyclic compounds in custom synthesis projects.
• Material Science Research: Investigated as a monomer or additive precursor for developing specialty polymers with unique optical or electronic properties.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies in fluoroorganic chemistry and asymmetric synthesis.

Basic Information

Product Name	2-(2-Fluoro-Benzoyl)-3-Oxo-Butyric Acid Ethyl Ester
CAS No.	677326-74-8
Molecular Formula	C13H13FO4
Molecular Weight	252.24 g/mol
Synonyms	Ethyl 2-(2-Fluorobenzoyl)-3-oxobutanoate; Ethyl 3-Oxo-2-(2-fluorobenzoyl)butyrate; 2-(2-Fluorobenzoyl)-3-oxobutyric Acid Ethyl Ester; 3-Oxo-2-(2-fluorobenzoyl)butyric Acid Ethyl Ester; 677326-74-8; 2-(2-Fluorobenzoyl)acetoacetic Acid Ethyl Ester; Ethyl (2-Fluorobenzoyl)acetoacetate
EINECS	Contact for details

Quality Control

Every batch of 2-(2-Fluoro-Benzoyl)-3-Oxo-Butyric Acid Ethyl Ester is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent lot-to-lot performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation by atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.