Description

n-((1R,2R)-2-Amino-1,2-Diphenylethyl)-1-(7,7-Dimethyl-2-Oxobicyclo[2.2.1]Heptan-1-Yl)Methanesulfonamide is a high-purity chiral sulfonamide derivative, serving as a critical advanced pharmaceutical intermediate and organocatalyst precursor. Its unique stereochemistry and functional groups make it invaluable for the asymmetric synthesis of complex molecules, enabling the production of enantiomerically pure active pharmaceutical ingredients (APIs). This compound is essential for R&D and manufacturing teams in the pharmaceutical, agrochemical, and fine chemical sectors seeking to develop novel therapeutics and high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of chiral drugs, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Asymmetric Organocatalyst: Precursor for novel chiral catalysts used in enantioselective synthesis, improving yield and purity in fine chemical production.
• Ligand for Metal Complexes: Used in the development of chiral ligands for transition metal catalysis, crucial for creating stereocenters in complex molecules.
• Agrochemical Research: Intermediate in the development of new, enantiomerically pure pesticides and herbicides with improved efficacy and environmental profiles.
• Academic & Industrial R&D: A valuable tool for methodological studies in organic synthesis and process chemistry within university and corporate laboratories.
• Custom Synthesis: Serves as a starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke compounds for clients.

Basic Information

Product Name	n-((1R,2R)-2-Amino-1,2-Diphenylethyl)-1-(7,7-Dimethyl-2-Oxobicyclo[2.2.1]Heptan-1-Yl)Methanesulfonamide
CAS No.	676270-67-0
Molecular Formula	C24H30N2O3S
Molecular Weight	426.57 g/mol
Synonyms	(1R,2R)-N-[(1R,2R)-2-Amino-1,2-diphenylethyl]-1-(7,7-dimethyl-2-oxobicyclo[2.2.1]hept-1-yl)methanesulfonamide; (1R,2R)-N-((1R,2R)-2-Amino-1,2-diphenylethyl)-1-(7,7-dimethyl-2-oxobicyclo[2.2.1]heptan-1-yl)methanesulfonamide; (1R,2R)-1-(7,7-Dimethyl-2-oxobicyclo[2.2.1]hept-1-yl)-N-[(1R,2R)-2-amino-1,2-diphenylethyl]methanesulfonamide; Chiral Camphorsulfonamide Derivative; (R,R)-TsDPEN Camphor Sulfonamide Analog
EINECS	Contact for details

Quality Control

Our n-((1R,2R)-2-Amino-1,2-Diphenylethyl)-1-(7,7-Dimethyl-2-Oxobicyclo[2.2.1]Heptan-1-Yl)Methanesulfonamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral HPLC for enantiomeric excess (ee) and standard purity assays, to ensure it meets the stringent requirements for pharmaceutical intermediates. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Maximum Impurity (HPLC)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.