Description

2,3,6-Trifluoroisonicotinic Acid is a high-value fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique trifluorinated structure offers enhanced metabolic stability and lipophilicity, making it indispensable for developing novel active compounds. This intermediate is primarily sought after by pharmaceutical and agrochemical research organizations for the creation of next-generation products.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and antiviral drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and pesticides, where the fluorine atoms contribute to biological activity and environmental persistence.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of fluorinated organic electronic materials and liquid crystals.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom fluorination projects and scale-up synthesis under cGMP or ISO standards.

Basic Information

Product Name	2,3,6-Trifluoroisonicotinic Acid
CAS No.	675602-92-3
Molecular Formula	C6H2F3NO2
Molecular Weight	177.08 g/mol
Synonyms	2,3,6-Trifluoropyridine-4-carboxylic Acid; 4-Pyridinecarboxylic Acid, 2,3,6-Trifluoro-; 2,3,6-Trifluoro-4-pyridinecarboxylic Acid; 2,3,6-Trifluoropyridine-4-carboxylic Acid; 2,3,6-Trifluoroisonicotinic Acid; 675602-92-3; Trifluorinated Isonicotinic Acid Derivative
EINECS	Contact for details

Quality Control

Every batch of 2,3,6-Trifluoroisonicotinic Acid is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and development. A Certificate of Analysis (COA) detailing identity, purity (typically by HPLC), and impurity profile is supplied with each shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong bases and oxidizing agents. Due to its acidic nature, appropriate chemical handling procedures should be followed.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.